In recent years, smart/stimuli-responsive hydrogels have drawn tremendous attention for
their varied applications, mainly in the biomedical field. These hydrogels are derived from …

Cartilage, especially articular cartilage, is a unique connective tissue consisting of
chondrocytes and cartilage matrix that covers the surface of joints. It plays a critical role in …

Osteochondral repair remains a challenge in clinical practice nowadays despite extensive
advances in tissue engineering. The insufficient recruitment of endogenous cells in the early …

The treatment of osteochondral defects (OCD) remains challenging. Among currently
available surgical treatments for OCDs, scaffold-based treatments are promising to …

Collagen, characteristic in biomimetic composition and hierarchical structure, boasts a huge
potential in repairing cartilage defect due to its extraordinary bioactivities and regulated …

The socioeconomic impact of osteochondral (OC) damage has been increasing steadily
over time in the global population, and the promise of tissue engineering in generating …

Background One of the main problems associated with the development of osteochondral
reparative materials is that the accurate imitation of the structure of the natural osteochondral …

Three-dimensional (3D) bioprinting is a novel technique applied to manufacture semisolid or
solid objects via deposition of successive thin layers. The widespread implementation of the …

Background: Press-fit Talar OsteoPeriostic grafting from the Iliac Crest (TOPIC) is a novel
technique for the treatment of large osteochondral lesions of the talus. The purpose of the …

The conventional methods of using autografts and allografts for repairing defects in bone,
the osteochondral bone, and the cartilage tissue have many disadvantages, like donor site …