[HTML][HTML] Genetics of malaria inflammatory responses: a pathogenesis perspective

C Penha-Gonçalves - Frontiers in immunology, 2019 - frontiersin.org
Despite significant progress in combating malaria in recent years the burden of severe
disease and death due to Plasmodium infections remains a global public health concern …

The host genetic diversity in malaria infection

VRR De Mendonça, MS Goncalves… - Journal of Tropical …, 2012 - Wiley Online Library
Populations exposed to Plasmodium infection develop genetic mechanisms of protection
against severe disease. The clinical manifestation of malaria results primarily from the lysis …

[HTML][HTML] Networking the host immune response in Plasmodium vivax malaria

VRR Mendonca, ATL Queiroz, FM Lopes, BB Andrade… - Malaria journal, 2013 - Springer
Background Plasmodium vivax malaria clinical outcomes are a consequence of the
interaction of multiple parasite, environmental and host factors. The host molecular and …

[HTML][HTML] Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features

D Marques, LR Ferreira-Costa… - World Journal of …, 2017 - ncbi.nlm.nih.gov
AIM To investigate the association between 16 insertion-deletions (INDEL) polymorphisms,
colorectal cancer (CRC) risk and clinical features in an admixed population. METHODS One …

Possible association of IL‐4 VNTR polymorphism with susceptibility to preeclampsia

S Salimi, M Mohammadoo-Khorasani… - BioMed research …, 2014 - Wiley Online Library
Preeclampsia (PE) is a pregnancy‐specific disorder that results in maternal mortality and
morbidity. Growing evidence indicated that cytokines are involved in the pathogenesis of PE …

Significant association of interleukin-4 gene intron 3 VNTR polymorphism with susceptibility to knee osteoarthritis

S Yigit, A Inanir, A Tekcan, E Tural, GT Ozturk… - Gene, 2014 - Elsevier
Abstract Objective Interleukin-4 (IL-4) is a strong chondroprotective cytokine and
polymorphisms within this gene may be a risk factor for osteoarthritis (OA). We aimed to …

The IL17F and IL17RA Genetic Variants Increase Risk of Cerebral Malaria in Two African Populations

S Marquet, I Conte, B Poudiougou, L Argiro… - Infection and …, 2016 - Am Soc Microbiol
Cerebral malaria (CM) is a neurological complication of infection with Plasmodium
falciparum that is partly caused by cytokine-mediated inflammation. It is not known whether …

[图书][B] Dynamic models of infectious diseases

VSH Rao, R Durvasula - 2013 - Springer
In Volume 1 of “Dynamic Models of Infectious Diseases,” ISBN 978-1-4614-3960-8 and 978-
1-4614-3961-5 (eBook), we assembled eight chapters from highly acclaimed international …

Overview of human genetic susceptibility to malaria: From parasitemia control to severe disease

S Marquet - Infection, Genetics and Evolution, 2018 - Elsevier
Malaria is a life-threatening blood disease caused by the protozoan Plasmodium. Infection
may lead to several different patterns of symptoms in the host: asymptomatic state …

Reduced parasite burden in children with falciparum malaria and bacteremia coinfections: role of mediators of inflammation

GC Davenport, JB Hittner, V Otieno… - Mediators of …, 2016 - Wiley Online Library
Bacteremia and malaria coinfection is a common and life‐threatening condition in children
residing in sub‐Saharan Africa. We previously showed that coinfection with Gram negative …