Both mitochondrial dysfunction and neuroinflammation are implicated in neurodegeneration
and neurodegenerative diseases. Accumulating evidence shows multiple links between …

Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …

Ferroptosis is a type of iron-dependent regulated cell death, representing an emerging
disease-modulatory mechanism. Transcription factors play multiple roles in ferroptosis …

Reactive oxygen species (ROS) plays a key role in therapeutic effects as well as side effects
of platinum drugs. Cisplatin mediates activation of nicotinamide adenine dinucleotide …

Microglia are critical nervous system‐specific immune cells serving as tissue‐resident
macrophages influencing brain development, maintenance of the neural environment …

Neuroinflammation and mitochondrial dysfunction are common features of chronic
neurodegenerative diseases of the central nervous system. Both conditions can lead to …

Iron dyshomeostasis can cause neuronal damage to iron-sensitive brain regions.
Neurodegeneration with brain iron accumulation reflects a group of disorders caused by iron …

Iron is required for the survival of most organisms, including bacteria, plants, and humans. Its
homeostasis in mammals must be fine-tuned to avoid iron deficiency with a reduced oxygen …

Astaxanthin is a carotenoid with powerful antioxidant and anti-inflammatory activity
produced by several freshwater and marine microorganisms, including bacteria, yeast, fungi …

Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease
(PD) enforce an overwhelming social and economic burden on society. They are primarily …