The diversity and complexity of the human brain are widely assumed to be encoded within a
constant genome. Somatic gene recombination, which changes germline DNA sequences to …

Retroviruses are the only group of viruses known to have left a fossil record, in the form of
endogenous proviruses, and approximately 8% of the human genome is made up of these …

Xenotransplantation of porcine organs might provide an unlimited source of donor organs to
treat endstage organ failure diseases in humans. However, pigs harbour retroviruses with …

High throughput screening, increased accuracy and the coupling of real-time quantitative
PCR (Q-PCR) to robotic set-up systems are beginning to revolutionise biotechnology …

Quantification of retroviruses in cell culture supernatants and other biological preparations is
required in a diverse spectrum of laboratories and applications. Methods based on antigen …

Three human cell lines used in human immunodeficiency virus research were found to be
contaminated with previously undetected retroviruses. On the bases of partial nucleotide …

PCR-enhanced reverse transcriptase assays (PERT) are sensitive tools for the detection of
retroviruses in biological samples. The adaptation of real-time PCR techniques based on …

The Sf9 cell line, derived from Spodoptera frugiperda, is used as a cell substrate for
biological products, and no viruses have been reported in this cell line after extensive …

Background: Retroviral involvement in amyotrophic lateral sclerosis (ALS) has been
suspected for several years since the recognition that both murine and human retroviruses …

Background: Retroviral involvement in the etiology of sporadic ALS has been suspected for
several years since the recognition that both murine and human retroviruses can cause …