The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9
single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta …

Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …

Cell-to-cell communication across multiple cell types and tissues strictly governs proper
functioning of metazoans and extensively relies on interactions between secreted ligands …

Memory for antigen is a defining feature of adaptive immunity. Antigen-specific lymphocyte
populations show an increase in number and function after antigen encounter and more …

After a century of controversy, the notion that the immune system regulates cancer
development is experiencing a new resurgence. An overwhelming amount of data from …

Follicular helper T (Tfh) cells provide selection signals to germinal center B cells, which is
essential for long-lived antibody responses. High CXCR5 and low CCR7 expression …

Even though osteoarthritis (OA) is mainly considered as a degradative condition of the
articular cartilage, there is increasing body of data demonstrating the involvement of all …

The immunotherapy of cancer has made significant strides in the past few years due to
improved understanding of the underlying principles of tumor biology and immunology …

The resurgence of tuberculosis worldwide has intensified research efforts directed at
examining the host defense and pathogenic mechanisms operative in Mycobacterium …

Abstract Interleukin 17 (IL-17)–producing T helper cells (TH-17 cells) have been
characterized in mice as a distinct subset of effector cells, but their identity and properties in …