Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …

Despite decades of intense research, the complex biology of glioblastoma (GBM) is not
completely understood. Progression-free survival and overall survival have remained …

Tumor-associated macrophages (TAMs) constitute a large population of glioblastoma and
facilitate tumor growth and invasion of tumor cells, but the underlying mechanism remains …

Integrins are a large family of transmembrane adhesion receptors, which play a key role in
interactions of a cell with the surrounding stroma. Integrins are comprised of non-covalently …

An outstanding characteristic of gliomas is their infiltration into brain parenchyma, a property
that impairs complete surgical resection; consequently, these tumors might recur, resulting in …

Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Three-dimensional visualization of tissue structures using optical microscopy facilitates the
understanding of biological functions. However, optical microscopy is limited in tissue …

A growing body of evidence suggests that long-chain non-coding RNA (lncRNA) plays an
important role in the malignant biological behavior and drug resistance of glioblastoma …

Epithelial-to-mesenchymal transition (EMT) and its reverse process MET naturally occur
during development and in tissue repair in vertebrates. EMT is also recognized as the …

Background: Epithelial-mesenchymal transition (EMT) is regulated by induction factors,
transcription factor families and an array of signaling pathways genes, and has been …