[HTML][HTML] The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis

N Gomez-Lopez, J Galaz, D Miller… - …, 2022 - rep.bioscientifica.com
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

[HTML][HTML] Placenta-derived exosomes as a modulator in maternal immune tolerance during pregnancy

K Bai, X Li, J Zhong, EHY Ng, WSB Yeung… - Frontiers in …, 2021 - frontiersin.org
Exosomes are a subset of extracellular vesicles with an average diameter of~ 100nm.
Exosomes are released by all cells through an endosome-dependent pathway and carry …

[HTML][HTML] Functional role of miR-155 in the pathogenesis of diabetes mellitus and its complications

SS Jankauskas, J Gambardella, C Sardu, A Lombardi… - Non-coding RNA, 2021 - mdpi.com
Substantial evidence indicates that microRNA-155 (miR-155) plays a crucial role in the
pathogenesis of diabetes mellitus (DM) and its complications. A number of clinical studies …

MicroRNA-155 and antiviral immune responses

A Jafarzadeh, A Naseri, L Shojaie, M Nemati… - International …, 2021 - Elsevier
The microRNA, miR-155 regulates both adaptive and innate immune responses. In viral
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …

Maternal and fetal T cells in term pregnancy and preterm labor

D Miller, M Gershater, R Slutsky, R Romero… - Cellular & Molecular …, 2020 - nature.com
Pregnancy is a state of immunological balance during which the mother and the developing
fetus must tolerate each other while maintaining sufficient immunocompetence to ward off …

[HTML][HTML] Recent highlights in the immunomodulatory aspects of Treg cell-derived extracellular vesicles: special emphasis on autoimmune diseases and transplantation

Y Asemani, S Najafi, F Ezzatifar, NM Zolbanin, R Jafari - Cell & bioscience, 2022 - Springer
In order to maintain immunological tolerance to self and non-self antigens, one's T
regulatory (Treg) cells play a critical role in the regulation of detrimental inflammation. Treg …

Cytokine imbalance at materno-embryonic interface as a potential immune mechanism for recurrent pregnancy loss

S Ali, S Majid, MN Ali, S Taing, MU Rehman… - International …, 2021 - Elsevier
Recurrent pregnancy loss (RPL) is a prominent reproductive disease that distresses about
2%-5% of couples. RPL is the loss of two or more successive spontaneous pregnancies …

[HTML][HTML] Early life stress detection using physiological signals and machine learning pipelines

Z Shahbazi, YC Byun - Biology, 2023 - mdpi.com
Simple Summary Problem statement: Stress is one of the challenges of human life that in
case of not curing may cause serious problems in human body. There are various type of …

[HTML][HTML] Adversity in early life and pregnancy are immunologically distinct from total life adversity: macrophage-associated phenotypes in women exposed to …

K Aschbacher, M Hagan, IM Steine, L Rivera… - Translational …, 2021 - nature.com
Early childhood and pregnancy are two sensitive periods of heightened immune plasticity,
when exposure to adversity may disproportionately increase health risks. However, we need …

[HTML][HTML] Toll-like receptor-4 null mutation causes fetal loss and fetal growth restriction associated with impaired maternal immune tolerance in mice

HY Chan, LM Moldenhauer, HM Groome… - Scientific Reports, 2021 - nature.com
Maternal immune adaptation to accommodate pregnancy depends on sufficient availability
of regulatory T (Treg) cells to enable embryo implantation. Toll-like receptor 4 is implicated …