Leveraging artificial intelligence in the fight against infectious diseases
Despite advances in molecular biology, genetics, computation, and medicinal chemistry,
infectious disease remains an ominous threat to public health. Addressing the challenges …
infectious disease remains an ominous threat to public health. Addressing the challenges …
Biotechnological methods to remove microplastics: a review
Microplastics pollution is major threat to ecosystems and is impacting abiotic and biotic
components. Microplastics are diverse and highly complex contaminants that transport other …
components. Microplastics are diverse and highly complex contaminants that transport other …
KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis
Gene set enrichment (GSE) analysis plays an essential role in extracting biological insight
from genome-scale experiments. ORA (overrepresentation analysis), FCS (functional class …
from genome-scale experiments. ORA (overrepresentation analysis), FCS (functional class …
PubChem in 2021: new data content and improved web interfaces
Abstract PubChem (https://pubchem. ncbi. nlm. nih. gov) is a popular chemical information
resource that serves the scientific community as well as the general public, with millions of …
resource that serves the scientific community as well as the general public, with millions of …
FlyBase: updates to the Drosophila melanogaster knowledge base
A Larkin, SJ Marygold, G Antonazzo… - Nucleic acids …, 2021 - academic.oup.com
FlyBase (flybase. org) is an essential online database for researchers using Drosophila
melanogaster as a model organism, facilitating access to a diverse array of information that …
melanogaster as a model organism, facilitating access to a diverse array of information that …
The MetaCyc database of metabolic pathways and enzymes-a 2019 update
R Caspi, R Billington, IM Keseler, A Kothari… - Nucleic acids …, 2020 - academic.oup.com
MetaCyc (MetaCyc. org) is a comprehensive reference database of metabolic pathways and
enzymes from all domains of life. It contains 2749 pathways derived from more than 60 000 …
enzymes from all domains of life. It contains 2749 pathways derived from more than 60 000 …
Opportunities and challenges of using metagenomic data to bring uncultured microbes into cultivation
Although there is now an extensive understanding of the diversity of microbial life on earth
through culture-independent metagenomic DNA sequence analyses, the isolation and …
through culture-independent metagenomic DNA sequence analyses, the isolation and …
Machine learning for metabolic engineering: A review
Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …
engineering more predictable. In this review, we offer an introduction to this discipline in …
A metabolic modeling platform for the computation of microbial ecosystems in time and space (COMETS)
Genome-scale stoichiometric modeling of metabolism has become a standard systems
biology tool for modeling cellular physiology and growth. Extensions of this approach are …
biology tool for modeling cellular physiology and growth. Extensions of this approach are …
Advancing computer-aided drug discovery (CADD) by big data and data-driven machine learning modeling
Highlights•Drug discovery has been advanced to a big data era with a large amount of
public data sources available.•Ten V features (volume, velocity, variety, veracity, validity …
public data sources available.•Ten V features (volume, velocity, variety, veracity, validity …