Hyperkalemia: pathophysiology, risk factors and consequences

RW Hunter, MA Bailey - Nephrology Dialysis Transplantation, 2019 - academic.oup.com
There have been significant recent advances in our understanding of the mechanisms that
maintain potassium homoeostasis and the clinical consequences of hyperkalemia. In this …

Treatment of urinary tract infections in the era of antimicrobial resistance and new antimicrobial agents

MS Bader, M Loeb, D Leto, AA Brooks - Postgraduate medicine, 2020 - Taylor & Francis
Urinary tract infections (UTIs) caused by antibiotic-resistant Gram-negative bacteria are a
growing concern due to limited treatment options. Knowledge of the common uropathogens …

Antibiotic management of urinary tract infection in elderly patients in primary care and its association with bloodstream infections and all cause mortality: population …

M Gharbi, JH Drysdale, H Lishman, R Goudie… - bmj, 2019 - bmj.com
Objective To evaluate the association between antibiotic treatment for urinary tract infection
(UTI) and severe adverse outcomes in elderly patients in primary care. Design Retrospective …

[HTML][HTML] Antimicrobial treatment and prophylaxis of plague: recommendations for naturally acquired infections and bioterrorism response

CA Nelson - MMWR. Recommendations and Reports, 2021 - cdc.gov
This report provides CDC recommendations to US health care providers regarding
treatment, pre-exposure prophylaxis, and postexposure prophylaxis of plague. Yersinia …

tICA-Metadynamics for Identifying Slow Dynamics in Membrane Permeation

M Oh, GCA Da Hora, JMJ Swanson - Journal of Chemical Theory …, 2023 - ACS Publications
Molecular simulations are commonly used to understand the mechanism of membrane
permeation of small molecules, particularly for biomedical and pharmaceutical applications …

The risk and clinical implications of antibiotic-associated acute kidney injury: a review of the clinical data for agents with signals from the food and drug administration's …

KM Clifford, AR Selby, KR Reveles, C Teng… - Antibiotics, 2022 - mdpi.com
Antibiotic-associated acute kidney injury (AA-AKI) is quite common, especially among
hospitalized patients; however, little is known about risk factors or mechanisms of why AA …

Lower urinary tract infections: management, outcomes and risk factors for antibiotic re-prescription in primary care

M Pujades-Rodriguez, RM West, MH Wilcox… - …, 2019 - thelancet.com
Summary Background Urinary tract infections (UTIs) are major drivers of antibiotic
prescribing in primary care. Inappropriate antibiotic prescribing for UTIs likely drives …

Management of urinary tract infections in direct to consumer telemedicine

R Rastogi, KA Martinez, N Gupta, M Rood… - Journal of general …, 2020 - Springer
Background Urinary tract infections (UTI) are a common reason for seeking care via direct to
consumer (DTC) telemedicine, yet patterns of care, including antibiotic prescribing, have not …

Bacterial vaccines for the management of recurrent urinary tract infections: a systematic review and meta-analysis

Q Mak, J Greig, P Dasgupta, S Malde, N Raison - European Urology Focus, 2024 - Elsevier
Background and objective Several bacterial immunisations have been developed to reduce
the socioeconomic burden of urinary tract infections (UTIs) and the use of prophylactic …

Hypothesis-Driven, Structure-Based Design in Photopharmacology: The Case of eDHFR Inhibitors

P Kobauri, NS Galenkamp, AM Schulte… - Journal of Medicinal …, 2022 - ACS Publications
Photopharmacology uses light to regulate the biological activity of drugs. This precise
control is obtained through the incorporation of molecular photoswitches into bioactive …