Wolbachia. Bacterial endosymbionts of filarial nematodes

MJ Taylor, C Bandi, A Hoerauf - Advances in parasitology, 2005 - Elsevier
Filarial nematodes are important helminth parasites of the tropics and a leading cause of
global disability. They include species responsible for onchocerciasis, lymphatic filariasis …

Wolbachia bacteria of filarial nematodes

MJ Taylor, A Hoerauf - Parasitology today, 1999 - cell.com
The finding that the intracellular bacteria of filarial nematodes are related to the Wolbachia
symbionts of arthropods has generated great interest. Here, Mark Taylor and Achim Hoerauf …

Class I. Alphaproteobacteria class. nov.

GM Garrity, JA Bell, T Lilburn - Bergey's manual® of systematic …, 2005 - Springer
Abstract Al. pha. pro. te. o. bac. te′ ri. a. Gr. n. alpha name of first letter of Greek alphabet;
Gr. n. Proteus ocean god able to change shape; Gr. n. bakterion a small rod; ML fem. pl. n …

Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: a double-blind, randomised placebo-controlled trial

MJ Taylor, WH Makunde, HF McGarry, JD Turner… - The Lancet, 2005 - thelancet.com
Background Wolbachia endosymbionts of filarial nematodes are vital for larval development
and adult-worm fertility and viability. This essential dependency on the bacterium for survival …

New Insights into the Evolution of Wolbachia Infections in Filarial Nematodes Inferred from a Large Range of Screened Species

E Ferri, O Bain, M Barbuto, C Martin, N Lo, S Uni… - PloS one, 2011 - journals.plos.org
Background Wolbachia are intriguing symbiotic endobacteria with a peculiar host range that
includes arthropods and a single nematode family, the Onchocercidae encompassing …

Wolbachia in filarial nematodes: evolutionary aspects and implications for the pathogenesis and treatment of filarial diseases

C Bandi, AJ Trees, NW Brattig - Veterinary parasitology, 2001 - Elsevier
The presence of intracellular bacteria in the body of various species of filarial nematodes,
including important parasites such as Brugia malayi, Dirofilaria immitis, and Onchocerca …

Inflammatory Responses Induced by the Filarial Nematode Brugia malayi Are Mediated by Lipopolysaccharide-like Activity from Endosymbiotic Wolbachia Bacteria

MJ Taylor, HF Cross, K Bilo - The Journal of experimental medicine, 2000 - rupress.org
The pathogenesis of filarial disease is characterized by acute and chronic inflammation.
Inflammatory responses are thought to be generated by either the parasite, the immune …

Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent …

NG Langworthy, A Renz… - … of the Royal …, 2000 - royalsocietypublishing.org
Filarial nematodes are important and widespread parasites of animals and humans. We
have been using the African bovine parasite Onchocerca ochengi as a chemotherapeutic …

Population dynamics of Wolbachia bacterial endosymbionts in Brugia malayi

HF McGarry, GL Egerton, MJ Taylor - Molecular and biochemical …, 2004 - Elsevier
The human filarial nematode Brugia malayi contains an endosymbiotic bacterium,
Wolbachia. We used real-time quantitative polymerase chain reaction (QPCR) and …

[HTML][HTML] Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

A Ehrens, A Hoerauf, MP Hübner - GMS Infectious Diseases, 2022 - ncbi.nlm.nih.gov
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected
Tropical Diseases and remain a public health problem in endemic countries. Lymphatic …