Antibiotic perturbations to the gut microbiome

SRS Fishbein, B Mahmud, G Dantas - Nature Reviews Microbiology, 2023 - nature.com
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

[HTML][HTML] Epidemiology of cholera

J Deen, MA Mengel, JD Clemens - Vaccine, 2020 - Elsevier
Cholera is an ancient disease that remains a public health problem in many impoverished
locations around the world. Seven pandemics of cholera have been recorded since the first …

Childhood diarrhoeal diseases in developing countries

HU Ugboko, OC Nwinyi, SU Oranusi, JO Oyewale - Heliyon, 2020 - cell.com
Diarrhoeal diseases collectively constitute a serious public health challenge globally,
especially as the leading cause of death in children (after respiratory diseases). Childhood …

Environmental parameters associated with incidence and transmission of pathogenic Vibrio spp.

KD Brumfield, M Usmani, KM Chen… - Environmental …, 2021 - Wiley Online Library
Vibrio spp. thrive in warm water and moderate salinity, and they are associated with aquatic
invertebrates, notably crustaceans and zooplankton. At least 12 Vibrio spp. are known to …

Genomic epidemiology reveals multidrug resistant plasmid spread between Vibrio cholerae lineages in Yemen

F Lassalle, S Al-Shalali, M Al-Hakimi, E Njamkepo… - Nature …, 2023 - nature.com
Since 2016, Yemen has been experiencing the largest cholera outbreak in modern history.
Multidrug resistance (MDR) emerged among Vibrio cholerae isolates from cholera patients …

Clinical surveillance systems obscure the true cholera infection burden in an endemic region

ST Hegde, AI Khan, J Perez-Saez, II Khan, JD Hulse… - Nature medicine, 2024 - nature.com
Our understanding of cholera transmission and burden largely relies on clinic-based
surveillance, which can obscure trends, bias burden estimates and limit the impact of …

Ongoing diphtheria outbreak in Yemen: a cross-sectional and genomic epidemiology study

E Badell, A Alharazi, A Criscuolo, KAA Almoayed… - The Lancet …, 2021 - thelancet.com
Background An outbreak of diphtheria, declared in Yemen in October, 2017, is ongoing. We
did a cross-sectional study to investigate the epidemiological, clinical, and microbiological …

Contrasting epidemiology of cholera in Bangladesh and Africa

DA Sack, AK Debes, J Ateudjieu, G Bwire… - The Journal of …, 2021 - academic.oup.com
Abstract In Bangladesh and West Bengal cholera is seasonal, transmission occurs
consistently annually. By contrast, in most African countries, cholera has inconsistent …

Genetic and biochemical mechanisms for bacterial lipid A modifiers associated with polymyxin resistance

H Zhang, S Srinivas, Y Xu, W Wei, Y Feng - Trends in biochemical sciences, 2019 - cell.com
Polymyxins are a group of detergent-like antimicrobial peptides that are the ultimate line of
defense against carbapenem-resistant pathogens in clinical settings. Polymyxin resistance …

Genomic attributes of Vibrio cholerae O1 responsible for 2022 massive cholera outbreak in Bangladesh

MM Monir, MT Islam, R Mazumder, D Mondal… - Nature …, 2023 - nature.com
In 2022, one of its worst cholera outbreaks began in Bangladesh and the icddr, b Dhaka
hospital treated more than 1300 patients and ca. 42,000 diarrheal cases from March-1 to …