The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

Transaminases (TAs) are one of the most promising biocatalysts in organic synthesis for the
preparation of chiral amino compounds. The concise reaction, excellent enantioselectivity …

Chiral amines are valuable building blocks for the pharmaceutical industry. ω-TAms have
emerged as an exciting option for their synthesis, offering a potential “green alternative” to …

Transaminases have attracted considerable interest in their use as biocatalysts for the
synthesis of compounds containing chiral amine units, which are widespread within the …

Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

The use of enzymes as catalysts for the preparation of novel compounds has received
steadily increasing attention over the past few years. High demands are placed on the …

Optically pure amines are highly valuable products or key intermediates for a vast number of
bioactive compounds; however, efficient methods for their preparation are rare. ω …

Enzymatic cascade reactions experience tremendous attention by cutting short conventional
step-by-step synthesis in a highly efficient and elegant fashion. Focusing on ω …

ω-Transaminases have been increasingly used as efficient biocatalysts due to their ability to
produce a wide range of optically pure amine compounds. Several approaches have been …

During the last decade the use of ω‐transaminases has been identified as a very powerful
method for the preparation of optically pure amines from the corresponding ketones. Their …