Skeletal muscles are essential for vital functions such as movement, postural support,
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …

Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

The adenosine triphosphate (ATP)-binding cassette efflux transporter G2 (ABCG2) was
originally discovered in a multidrug-resistant breast cancer cell line. Studies in the past have …

Skeletal muscle possesses remarkable regenerative potential due to satellite cells, an injury-
responsive stem cell population located beneath the muscle basal lamina that expresses …

Skeletal muscle, a tissue endowed with remarkable endogenous regeneration potential, is
still under focused experimental investigation mainly due to treatment potential for muscle …

The morpho-functional recovery of injured skeletal muscle still represents an unmet need.
None of the therapeutic options so far adopted have proved to be resolutive. A current …

Immune surveillance in tissues is mediated by a long-lived subset of tissue-resident memory
T cells (Trm cells). A putative subset of tissue-resident long-lived stem cells is characterized …

Adult skeletal muscle can regenerate effectively after mild physical or chemical insult.
Muscle trauma or disease can overwhelm this innate capacity for regeneration and result in …

Tissue-specific stem cells are found throughout the body and, with proper intervention and
environmental cues, these stem cells exercise their capabilities for differentiation into …

The musculoskeletal system includes tissues that have remarkable regenerative
capabilities. Bone and muscle sustain micro-damage throughout the lifetime, yet they …