Pathogenesis of progressive multifocal leukoencephalopathy and risks associated with treatments for multiple sclerosis: a decade of lessons learned
EO Major, TA Yousry, DB Clifford - The Lancet Neurology, 2018 - thelancet.com
Progressive multifocal leukoencephalopathy (PML) is a rare, devastating demyelinating
disease of the CNS caused by the JC virus (JCV) that occurs in patients with compromised …
disease of the CNS caused by the JC virus (JCV) that occurs in patients with compromised …
Progressive multifocal leukoencephalopathy and other forms of JC virus disease
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the brain
caused by the JC virus (JCV). PML usually occurs via reactivation of JCV when an immune …
caused by the JC virus (JCV). PML usually occurs via reactivation of JCV when an immune …
Diagnosis of central nervous system complications in HIV-infected patients: cerebrospinal fluid analysis by the polymerase chain reaction
Neurological complications afflict the majority of people who are infected with HIV. These
include opportunistic infections, tumours, vascular and metabolic complications, and also …
include opportunistic infections, tumours, vascular and metabolic complications, and also …
Analysis of the systemic and intrathecal humoral immune response in progressive multifocal leukoencephalopathy
Progressive multifocal leukoencephalopathy (PML) is a subacute viral infection of
oligodendrocytes by JC virus occurring almost exclusively in immunocompromised patients …
oligodendrocytes by JC virus occurring almost exclusively in immunocompromised patients …
Progressive multifocal leukoencephalopathy
T Weber - Neurologic clinics, 2008 - Elsevier
Progessive mulifocal leukoencephalopathy (PML) incidence has increased about fivefold
due to the AIDS pandemic. The disease has an insidious onset with HIV infection as …
due to the AIDS pandemic. The disease has an insidious onset with HIV infection as …
JC virus antibody status underestimates infection rates
JR Berger, SA Houff, J Gurwell, N Vega… - Annals of …, 2013 - Wiley Online Library
Objective JC virus (JCV) seropositivity is a risk factor for progressive multifocal
leukoencephalopathy (PML) in patients on natalizumab. Accordingly, the JCV serological …
leukoencephalopathy (PML) in patients on natalizumab. Accordingly, the JCV serological …
Disappearance of cerebrospinal fluid oligoclonal bands after natalizumab treatment of multiple sclerosis patients
F von Glehn, AS Farias… - Multiple Sclerosis …, 2012 - journals.sagepub.com
Intrathecal immunoglobulin synthesis in an oligoclonal pattern is the most common
immunologic abnormality detected in MS patients. Various treatments, such as …
immunologic abnormality detected in MS patients. Various treatments, such as …
Progressive multifocal leukoencephalopathy in multiple sclerosis
JJ Chalkley, JR Berger - Current neurology and neuroscience reports, 2013 - Springer
AIDS generated a significantly increased interest in the pathogenesis, clinical
manifestations, and treatment of progressive multifocal leukoencephalopathy (PML), a …
manifestations, and treatment of progressive multifocal leukoencephalopathy (PML), a …
[HTML][HTML] The pathogenesis of progressive multifocal leukoencephalopathy
JR Berger, K Khalili - Discovery medicine, 2011 - discoverymedicine.com
Interest in pathogenesis of progressive multifocal leukoencephalopathy (PML) followed the
observation of the high risk for the disease in HIV infection and the recent observation of an …
observation of the high risk for the disease in HIV infection and the recent observation of an …
Prevalence of long‐term BK and JC excretion in HIV‐infected adults and lack of correlation with serological markers
WA Knowles, D Pillay, MA Johnson… - Journal of medical …, 1999 - Wiley Online Library
The natural history of polyomavirus infection, and sensitivity of diagnostic assays remain
unclear. A stratified group of 94 human immunodeficiency virus (HIV)‐infected patients was …
unclear. A stratified group of 94 human immunodeficiency virus (HIV)‐infected patients was …