Environmentally sustainable DRS-FTIR probe assisted by chemometric tools for quality control analysis of cinnarizine and piracetam having diverged concentration …
A novel diffuse reflectance fourier transform infrared spectroscopic method accompanied by
chemometrics was optimized to fulfill the white analytical chemistry and green analytical …
chemometrics was optimized to fulfill the white analytical chemistry and green analytical …
Novel Gastroprotective and Thermostable Cocrystal of Dimethyl Fumarate: Its Preparation, Characterization, and In Vitro and In Vivo Evaluation
Q Alam, A Ganeshpurkar, SK Singh… - ACS …, 2023 - ACS Publications
Crystallization has revolutionized the field of solid-state formulations by modulating the
physiochemical and release profile of active pharmaceutical ingredients (APIs). Dimethyl …
physiochemical and release profile of active pharmaceutical ingredients (APIs). Dimethyl …
A novel phenylpyrrolidine derivative: synthesis and effect on cognitive functions in rats with experimental ishemic stroke
DA Borozdenko, AA Ezdoglian, TA Shmigol… - Molecules, 2021 - mdpi.com
We performed an in silico, in vitro, and in vivo assessment of a potassium 2-[2-(2-oxo-4-
phenylpyrrolidin-1-yl) acetamido] ethanesulfonate (compound 1) as a potential prodrug for …
phenylpyrrolidin-1-yl) acetamido] ethanesulfonate (compound 1) as a potential prodrug for …
[HTML][HTML] New therapeutic activity of metabolic enhancer piracetam in treatment of neurodegenerative disease: Participation of caspase independent death factors …
Piracetam, a nootropic drug that has been clinically used for decades but remains enigmatic
due to no distinct understanding of its mechanism of action. The present study aimed to …
due to no distinct understanding of its mechanism of action. The present study aimed to …
Indole-3-carbinol improves neurobehavioral symptoms in a cerebral ischemic stroke model
Stroke is one of the most common causes of death worldwide and also responsible for
permanent disability. Ischemic stroke has been found to affect 80% of stroke patients …
permanent disability. Ischemic stroke has been found to affect 80% of stroke patients …
Pharmacokinetics and brain penetration study of chlorogenic acid in rats
The present study is designed to investigate the brain distribution and plasma
pharmacokinetics profiles of chlorogenic acid (CGA) after intranasal administration in …
pharmacokinetics profiles of chlorogenic acid (CGA) after intranasal administration in …
Ameliorative effects of 6‑gingerol in cerebral ischemia are mediated via the activation of antioxidant and anti‑inflammatory pathways
R Kongsui, J Jittiwat - Biomedical Reports, 2023 - spandidos-publications.com
Focal ischemia occurs when an embolus or thrombus occludes an artery, causing the rapid
obstruction of cerebral blood flow. Although stroke represents a main cause of disability and …
obstruction of cerebral blood flow. Although stroke represents a main cause of disability and …
Pharmacological application of barium containing bioactive glass in gastro-duodenal ulcers
Peptic ulcer is prevalent in about 4% of the world population and nearly 10% of people have
been affected by peptic ulcer at some point in their life. Therefore, there is a need for newer …
been affected by peptic ulcer at some point in their life. Therefore, there is a need for newer …
Preparation, Characterization, in-vitro and in-vivo Pharmacokinetic Evaluation of Thermostable Dimethyl Fumarate Cocrystals
Dimethyl fumarate (DMF) is an FDA-approved drug for treating relapsing-remitting multiple
sclerosis; but it is susceptible to sublimation leading to its loss during processing. Cocrystals …
sclerosis; but it is susceptible to sublimation leading to its loss during processing. Cocrystals …
The conditions under which piracetam is used and the factors that can improve National Institute of Health Stroke Scale Score in ischemic stroke patients and the …
SY Chen, JW Liu, YH Wang, JY Huang… - Journal of Clinical …, 2019 - mdpi.com
This study aimed to explore the associations of piracetam use and the clinical characteristics
of NIHSS (National Institute of Health Stroke Scale) changes—the importance of which, as …
of NIHSS (National Institute of Health Stroke Scale) changes—the importance of which, as …