The diagnosis, classification, and treatment of sarcoma in this era of artificial intelligence and immunotherapy

A Crombé, M Roulleau‐Dugage… - Cancer …, 2022 - Wiley Online Library
Soft‐tissue sarcomas (STS) represent a group of rare and heterogeneous tumors associated
with several challenges, including incorrect or late diagnosis, the lack of clinical expertise …

[HTML][HTML] Radiomics and artificial intelligence for soft-tissue sarcomas: Current status and perspectives

A Crombé, P Spinnato, A Italiano, HJ Brisse… - Diagnostic and …, 2023 - Elsevier
This article proposes a summary of the current status of the research regarding the use of
radiomics and artificial intelligence to improve the radiological assessment of patients with …

MRI-based delta-radiomics predicts pathologic complete response in high-grade soft-tissue sarcoma patients treated with neoadjuvant therapy

JC Peeken, R Asadpour, K Specht, EY Chen… - Radiotherapy and …, 2021 - Elsevier
Purpose In high-grade soft-tissue sarcomas (STS) the standard of care encompasses
multimodal therapy regimens. While there is a growing body of evidence for prognostic …

Development and external validation of deep-learning-based tumor grading models in soft-tissue sarcoma patients using MR imaging

F Navarro, H Dapper, R Asadpour, C Knebel… - Cancers, 2021 - mdpi.com
Simple Summary In soft-tissue sarcoma (STS) patients, the decision for the optimal treatment
modality largely depends on STS size, location, and a pathological measure that assesses …

Systematic review of sarcomas radiomics studies: Bridging the gap between concepts and clinical applications?

A Crombé, D Fadli, A Italiano, O Saut, X Buy… - European Journal of …, 2020 - Elsevier
Objectives Sarcomas are a model for intra-and inter-tumoral heterogeneities making them
particularly suitable for radiomics analyses. Our purposes were to review the aims, methods …

Intensity harmonization techniques influence radiomics features and radiomics-based predictions in sarcoma patients

A Crombé, M Kind, D Fadli, F Le Loarer, A Italiano… - Scientific Reports, 2020 - nature.com
Intensity harmonization techniques (IHT) are mandatory to homogenize multicentric MRIs
before any quantitative analysis because signal intensities (SI) do not have standardized …

CT and MRI radiomics of bone and soft-tissue sarcomas: a systematic review of reproducibility and validation strategies

S Gitto, R Cuocolo, D Albano, F Morelli… - Insights Into …, 2021 - Springer
Background Feature reproducibility and model validation are two main challenges of
radiomics. This study aims to systematically review radiomic feature reproducibility and …

Distinct patterns of the natural evolution of soft tissue sarcomas on pre-treatment MRIs captured with delta-radiomics correlate with gene expression profiles

A Crombé, F Bertolo, D Fadli, M Kind, F Le Loarer… - European …, 2023 - Springer
Objectives Radiomics of soft tissue sarcomas (STS) is assumed to correlate with histologic
and molecular tumor features, but radiogenomics analyses are lacking. Our aim was to …

Multi-parametric MRI-based radiomics for the diagnosis of malignant soft-tissue tumor

Z Yue, X Wang, T Yu, S Shang, G Liu, W Jing… - Magnetic Resonance …, 2022 - Elsevier
Purpose To develop and validate a multiparametric magnetic resonance imaging-based
radiomics nomogram for differentiating malignant and benign soft-tissue tumors. Methods A …

Radiofrequency ablation of lung metastases of colorectal cancer: could early radiomics analysis of the ablation zone help detect local tumor progression?

A Crombé, J Palussière, V Catena… - The British Journal of …, 2023 - academic.oup.com
Objectives: To determine whether radiomics data can predict local tumor progression (LTP)
following radiofrequency ablation (RFA) of colorectal cancer (CRC) lung metastases on the …