Metabolic reprogramming in modulating T cell reactive oxygen species generation and antioxidant capacity

JN Rashida Gnanaprakasam, R Wu… - Frontiers in …, 2018 - frontiersin.org
A robust adaptive immune response requires a phase of proliferative burst which is followed
by the polarization of T cells into relevant functional subsets. Both processes are associated …

Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation

G Lian, JNR Gnanaprakasam, T Wang, R Wu, X Chen… - elife, 2018 - elifesciences.org
Upon antigen stimulation, T lymphocytes undergo dramatic changes in metabolism to fulfill
the bioenergetic, biosynthetic and redox demands of proliferation and differentiation …

[HTML][HTML] High-glutathione producing yeasts obtained by genetic improvement strategies: a focus on adaptive evolution approaches for novel wine strains

L De Vero, T Bonciani, A Verspohl, F Mezzetti… - AIMS …, 2017 - ncbi.nlm.nih.gov
Glutathione (GSH) is the most abundant non-protein thiol in living organisms. Due to its
important antioxidant role, it is widely used in medicine, as a food additive, and in the …

The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae

D Ganguli, C Kumar, AK Bachhawat - Genetics, 2007 - academic.oup.com
Abstract Glutathione (GSH), l-γ-glutamyl-l-cysteinyl-glycine, is the major low-molecular-
weight thiol compound present in almost all eukaryotic cells. GSH degradation proceeds …

Glutathione production in yeast

AK Bachhawat, D Ganguli, J Kaur, N Kasturia… - Yeast biotechnology …, 2009 - Springer
Glutathione, γ-glutamyl-cysteinyl-glycine, is the most abundant non-protein thiol found in
almost all eukaryotic cells (and in some prokaryotes). The tripeptide, which is synthesized …

Glutathione as a prebiotic answer to α-peptide based life

B Fiser, B Jójárt, M Szőri, G Lendvay… - The Journal of …, 2015 - ACS Publications
The energetics of peptide bond formation is an important factor not only in the design of
chemical peptide synthesis, but it also has a role in protein biosynthesis. In this work …

Quantum Chemical Calculations on Small Protein Models

I Jákli, A Perczel, B Viskolcz, IG Csizmadia - Protein Modelling, 2014 - Springer
After the definition of the peptide bond and its strength, as measured by its amidicity values
the Ramachandran type potential energy surface (PES) of the backbone was investigated …

[引用][C] Enhancing oral delivery of glutathione using chitosan nanoparticles

ZA Alobaidy - 2013 - … of Petra, Faculty of Pharmacy and …