Host-response patterns of intramammary infections in dairy cows

YH Schukken, J Günther, J Fitzpatrick… - Veterinary immunology …, 2011 - Elsevier
Many different bacterial species have the ability to cause an infection of the bovine
mammary gland and the host response to these infections is what we recognize as mastitis …

Bovine mastitis: frontiers in immunogenetics

K Thompson-Crispi, H Atalla, F Miglior… - Frontiers in …, 2014 - frontiersin.org
Mastitis is one of the most prevalent and costly diseases in the dairy industry with losses
attributable to reduced milk production, discarded milk, early culling, veterinary services, and …

Escherichia coli, but not Staphylococcus aureus triggers an early increased expression of factors contributing to the innate immune defense in the udder of the cow

W Petzl, H Zerbe, J Günther, W Yang, HM Seyfert… - Veterinary …, 2008 - hal.science
The outcome of an udder infection is influenced by the pathogen species. We established a
strictly defined infection model to better analyze the unknown molecular causes for these …

Investigating the Immunological and Biological Equilibrium of Reservoir Hosts and Pathogenic Leptospira: Balancing the Solution to an Acute Problem?

EJ Putz, JE Nally - Frontiers in microbiology, 2020 - frontiersin.org
Leptospirosis is a devastating zoonotic disease affecting people and animals across the
globe. Pathogenic leptospires are excreted in urine of reservoir hosts which directly or …

Infection, immunity and the neuroendocrine response

P Borghetti, R Saleri, E Mocchegiani, A Corradi… - Veterinary Immunology …, 2009 - Elsevier
The Central Nervous (CNS) and Immune Systems (IS) are the two major adaptive systems
which respond rapidly to numerous challenges that are able to compromise health. The …

Experimental Staphylococcus aureus infection of the mammary gland induces region-specific changes in innate immune gene expression

CJ Whelehan, KG Meade, PD Eckersall… - Veterinary immunology …, 2011 - Elsevier
Staphylococcus aureus is a prolific mastitis-causing bacterium that resides naturally in the
environment of the dairy cow. The aim of this study was to profile immune gene expression …

Neospora caninum infection during early pregnancy in cattle: how the isolate influences infection dynamics, clinical outcome and peripheral and local immune …

J Regidor-Cerrillo, D Arranz-Solís, J Benavides… - Veterinary …, 2014 - Springer
This work studies the influence of Neospora caninum intra-species diversity on abortion
outcome, infection dynamics in terms of parasite dissemination and peripheral-local immune …

Monocyte and macrophage heterogeneity and Toll-like receptors in the lung

D Schneberger, K Aharonson-Raz, B Singh - Cell and tissue research, 2011 - Springer
Mononuclear phagocytes are crucial components of the innate host defense system. Cells
such as macrophages and monocytes phagocytose and process pathogens, produce …

Toll-like receptors and their role in animal reproduction

TR Kannaki, M Shanmugam, PC Verma - Animal reproduction science, 2011 - Elsevier
Toll-like receptors (TLRs) are evolutionarily conserved innate immune receptors that
recognize pathogen specific molecular pattern (PAMPs) in an efficient, non-self-reactive …

Targeting TLR2 for vaccine development

AP Basto, A Leitão - Journal of immunology research, 2014 - Wiley Online Library
Novel and more effective immunization strategies against many animal diseases may profit
from the current knowledge on the modulation of specific immunity through stimulation of …