Alveolar epithelial cells: master regulators of lung homeostasis

L Guillot, N Nathan, O Tabary, G Thouvenin… - The international journal …, 2013 - Elsevier
The lung interfaces with the environment across a continuous epithelium composed of
various cell types along the proximal and distal airways. At the alveolar structure level, the …

Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction

S Herold, NM Gabrielli, I Vadász - American Journal of …, 2013 - journals.physiology.org
In this review we summarize recent major advances in our understanding on the molecular
mechanisms, mediators, and biomarkers of acute lung injury (ALI) and alveolar-capillary …

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis

EP Schmidt, Y Yang, WJ Janssen, A Gandjeva… - Nature medicine, 2012 - nature.com
Sepsis, a systemic inflammatory response to infection, commonly progresses to acute lung
injury (ALI), an inflammatory lung disease with high morbidity. We postulated that sepsis …

Mechanisms of attenuation of abdominal sepsis induced acute lung injury by ascorbic acid

BJ Fisher, D Kraskauskas, EJ Martin… - … of Physiology-Lung …, 2012 - journals.physiology.org
Bacterial infections of the lungs and abdomen are among the most common causes of
sepsis. Abdominal peritonitis often results in acute lung injury (ALI). Recent reports …

Gut–lung crosstalk during critical illness

S Nath, GD Kitsios, LDJ Bos - Current Opinion in Critical Care, 2023 - journals.lww.com
Gut–lung crosstalk during critical illness : Current Opinion in Critical Care Gut–lung
crosstalk during critical illness : Current Opinion in Critical Care Log in or Register …

Advances in understanding of the pathogenesis of acute respiratory distress syndrome

C Sharp, AB Millar, ARL Medford - Respiration, 2015 - karger.com
The clinical syndrome of acute lung injury (ALI) occurs as a result of an initial acute systemic
inflammatory response. This can be consequent to a plethora of insults, either direct to the …

Post resusicitation fluid boluses in severe sepsis or septic shock: prevalence and efficacy (price study)

S Bihari, S Prakash, AD Bersten - Shock, 2013 - journals.lww.com
Objective To estimate the prevalence and efficacy of FBs after initial resuscitation in septic
patients. Methods In a prospective study, patients with severe sepsis/septic shock were …

Human adult bone marrow-derived stem cells decrease severity of lipopolysaccharide-induced acute respiratory distress syndrome in sheep

M Rojas, N Cárdenes, E Kocyildirim, JR Tedrow… - Stem cell research & …, 2014 - Springer
Introduction Acute respiratory distress syndrome (ARDS) is the most common cause of
respiratory failure among critically ill subjects, sepsis and severe bacterial pneumonia being …

Infusion of freshly isolated autologous bone marrow derived mononuclear cells prevents endotoxin-induced lung injury in an ex-vivo perfused swine model

M Rojas, RE Parker, N Thorn, C Corredor… - Stem cell research & …, 2013 - Springer
Introduction The acute respiratory distress syndrome (ARDS), affects up to 150,000 patients
per year in the United States. We and other groups have demonstrated that bone marrow …

Mechanistic understanding of lung inflammation: recent advances and emerging techniques

C Keskinidou, AG Vassiliou, I Dimopoulou… - Journal of …, 2022 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is a life-threatening lung injury characterized by
an acute inflammatory response in the lung parenchyma. Hence, it is considered as the most …