Antitubercular properties of thiazolidin-4-ones–A review

N Trotsko - European Journal of Medicinal Chemistry, 2021 - Elsevier
Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …

Synthesis of pyridine derivatives for diverse biological activity profiles: a review

TR Allaka, NK Katari - Recent Developments in the Synthesis and …, 2023 - Elsevier
Pyridine (py) is one of the important heterocyclic compounds and an internal part of several
natural products. There are various medicines containing pyridine ring system being …

Synthesis, antimycobacterial activity and docking study of 2-aroyl-[1] benzopyrano [4, 3-c] pyrazol-4 (1H)-one derivatives and related hydrazide-hydrazones

VT Angelova, V Valcheva, T Pencheva… - Bioorganic & Medicinal …, 2017 - Elsevier
A new convenient method for preparation of 2-aroyl-[1] benzopyrano [4, 3-c] pyrazol-4 (1H)-
one derivatives 5b–g and coumarin containing hydrazide-hydrazone analogues 4a–e was …

Studies on isoniazid derivatives through a medicinal chemistry approach for the identification of new inhibitors of urease and inflammatory markers

F Rizvi, M Khan, A Jabeen, H Siddiqui… - Scientific Reports, 2019 - nature.com
A library of thiosemicarbazide derivatives of isoniazid 3–27, was synthesized and evaluated
for their anti-inflammatory and urease inhibition activities, by using in vitro bioassays. Among …

New indole and indazole derivatives as potential antimycobacterial agents

VT Angelova, T Pencheva, N Vassilev… - Medicinal Chemistry …, 2019 - Springer
The study reports on the synthesis and in vitro assessment of the antimycobacterial activity
of a series of new indole-and indazole-based aroylhydrazones evaluated against …

Synthesis, antimycobacterial screening, molecular docking, ADMET prediction and pharmacological evaluation on novel pyran-4-one bearing hydrazone, triazole and …

N Ravisankar, N Sarathi, T Maruthavanan… - Journal of Molecular …, 2023 - Elsevier
The respiratory infection tuberculosis is caused by the bacteria Mycobacterium tuberculosis
and its unrelenting spread caused millions of deaths around the world. Hence, it is needed …

2-Thiophenecarboxylic acid hydrazide derivatives: synthesis and anti-tuberculosis studies

MRG Fahmi, L Khumaidah, TK Ilmiah… - IOP Conference …, 2018 - iopscience.iop.org
One of the most frequent and widespread infectious diseases especially in developing
countries is tuberculosis (TB). The number of TB drug resistant tend to increase, and there …

Ecofriendly synthesis and biological evaluation of 4-(4-nitro-phenyl)-2-phenyl-1, 4-dihydro-benzo [4, 5] imidazo [1, 2-a] pyrimidine-3-carboxylic acid ethyl ester …

PP Warekar, PT Patil, KT Patil, DK Jamale… - Synthetic …, 2016 - Taylor & Francis
An ecofriendly route has been investigated for the synthesis of 4-(4-nitro-phenyl)-2-phenyl-1,
4-dihydro-benzo [4, 5] imidazo [1, 2-a] pyrimidine-3-carboxylic acid ethyl ester derivatives by …

Complexation study of synthesized pharmacological organic ligands with samarium

ZT Omar, S Jadhav, M Mohsin, AS Faizaa… - Russian journal of …, 2020 - Springer
This research describes the formation of samarium complexation with organic ligands (Schiff
bases of anti-mycobacterial agent isonicotinic acid hydrazide) through pH-metric technique …

Potentiometric and Thermodynamic Studies of (N-[-(4-Chlorophenyl) Methylene]Nicotinohydrazide) and Its Transition Metal Complexes

ZT Omar, S Jadhav, M Rai - Integrated Ferroelectrics, 2020 - Taylor & Francis
Pharmacologically active organic ligands (N-[-(4-chlorophenyl) methylene]
nicotinohydrazide) synthesized through the condensation of equimolar mixture of anti …