[HTML][HTML] Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
E Larrañeta, REM Lutton, AD Woolfson… - Materials Science and …, 2016 - Elsevier
Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …
Polymeric microneedles for transdermal protein delivery
The intrinsic properties of therapeutic proteins generally present a major impediment for
transdermal delivery, including their relatively large molecule size and susceptibility to …
transdermal delivery, including their relatively large molecule size and susceptibility to …
[HTML][HTML] Recent approaches for enhancing the performance of dissolving microneedles in drug delivery applications
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
Transdermal delivery of drugs with microneedles—potential and challenges
K Ita - Pharmaceutics, 2015 - mdpi.com
Transdermal drug delivery offers a number of advantages including improved patient
compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre …
compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre …
Microneedles: a new frontier in nanomedicine delivery
This review aims to concisely chart the development of two individual research fields,
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …
Materials for immunotherapy
Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …
preclinical studies. The interplay of chemistry and materials has resulted in improved …
Progress and perspective of microneedle system for anti-cancer drug delivery
Transdermal drug delivery exhibited encouraging prospects, especially through superficial
drug administration routes. However, only a few limited lipophilic drug molecules could …
drug administration routes. However, only a few limited lipophilic drug molecules could …
Microneedle system for transdermal drug and vaccine delivery: devices, safety, and prospects
X He, J Sun, J Zhuang, H Xu, Y Liu, D Wu - Dose-response, 2019 - journals.sagepub.com
Microneedle (MN) delivery system has been greatly developed to deliver drugs into the skin
painlessly, noninvasively, and safety. In the past several decades, various types of MNs …
painlessly, noninvasively, and safety. In the past several decades, various types of MNs …
Smart vaccine delivery based on microneedle arrays decorated with ultra-pH-responsive copolymers for cancer immunotherapy
Despite the tremendous potential of DNA-based cancer vaccines, their efficacious delivery
to antigen presenting cells to stimulate both humoral and cellular response remains a major …
to antigen presenting cells to stimulate both humoral and cellular response remains a major …
Enhanced Cancer Vaccination by In Situ Nanomicelle-Generating Dissolving Microneedles
Efficient delivery of tumor antigens and immunostimulatory adjuvants into lymph nodes is
crucial for the maturation and activation of antigen-presenting cells (APCs), which …
crucial for the maturation and activation of antigen-presenting cells (APCs), which …