Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes

R Gomez-Casal, C Bhattacharya, N Ganesh, L Bailey… - Molecular cancer, 2013 - Springer
Ionizing radiation (IR) is used for patients diagnosed with unresectable non small cell lung
cancer (NSCLC), however radiotherapy remains largely palliative due to radioresistance …

Epigallocatechin-3-gallate inhibits nicotine‑induced migration and invasion by the suppression of angiogenesis and epithelial‑mesenchymal transition in non-small …

J Shi, F Liu, W Zhang, X Liu, B Lin… - Oncology …, 2015 - spandidos-publications.com
Abstract Epigallocatechin-3-gallate (EGCG), the most abundant polyphenol in green tea
extract, has been found to have anticancer activities in various types of cancer. However, the …

[PDF][PDF] Hypothesis of opposite interplay between the canonical WNT/beta-catenin pathway and PPAR gamma in primary central nervous system lymphomas

A Vallée, Y Lecarpentier, JN Vallée - Current Issues in Molecular …, 2019 - caister.com
Primary central nervous system lymphomas (PCNSLs) are angiocentric neoplasia which
present dense monoclonal lymphocyte proliferation, and occur in brain parenchyma in 90 …

Analysis of genes associated with prognosis of lung adenocarcinoma based on GEO and TCGA databases

Y Yu, X Tian - Medicine, 2020 - journals.lww.com
Methods: The gene expression data for GSE118370 was downloaded from the Gene
Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) between …

Implications of NOVA1 suppression within the microenvironment of gastric cancer: association with immune cell dysregulation

EK Kim, SO Yoon, WY Jung, H Lee, Y Kang, YJ Jang… - Gastric cancer, 2017 - Springer
Background The neuronal splicing factor neuro-oncological ventral antigen 1 (NOVA1) is
enriched in normal fibroblasts. Stromal spindle cells such as fibroblasts are major …

FGFR1 amplification is associated with poor prognosis and smoking in non-small-cell lung cancer

AN Seo, Y Jin, HJ Lee, PL Sun, H Kim, S Jheon, K Kim… - Virchows Archiv, 2014 - Springer
FGFR1 amplification has been identified recently as an important therapeutic target in non-
small-cell lung cancer (NSCLC), particularly squamous cell carcinoma (SqCC). However …

Clinicopathological significance and prognostic value of E-cadherin expression in non-small cell lung cancer: a protocol for systematic review and meta-analysis

D Chao, G Hu, Q Li - Medicine, 2021 - journals.lww.com
Background: E-cadherin, a calcium-dependent cell adhesion molecule, as an important
mediator of adhesion and signaling pathway, plays a key role in maintaining tissue integrity …

[HTML][HTML] Prognostic significance of stem cell-related marker expression and its correlation with histologic subtypes in lung adenocarcinoma

E Park, SY Park, PL Sun, Y Jin, JE Kim, S Jheon… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) are a small subset of tumor cells that exhibit stem cell-like
properties and contribute in treatment failure. To clarify the expression and prognostic …

Clinicopathologic and prognostic significance of c-MYC copy number gain in lung adenocarcinomas

AN Seo, JM Yang, H Kim, S Jheon, K Kim… - British journal of …, 2014 - nature.com
Background: c-MYC copy number gain (c-MYC gain) has been associated with aggressive
behaviour in several cancers. However, the role of c-MYC gain has not yet been determined …

Prognostic and clinicopathological significance of downregulated E-cadherin expression in patients with non-small cell lung cancer (NSCLC): a meta-analysis

YL Yang, MW Chen, L Xian - PloS one, 2014 - journals.plos.org
Background Many studies have investigated the prognostic role of E-cadherin in patients
with NSCLC; however, the result still remains inconclusive. An up-to data system review and …