Application of text mining in the biomedical domain

WWM Fleuren, W Alkema - Methods, 2015 - Elsevier
In recent years the amount of experimental data that is produced in biomedical research and
the number of papers that are being published in this field have grown rapidly. In order to …

Biomedical text categorization based on ensemble pruning and optimized topic modelling

A Onan - Computational and Mathematical Methods in …, 2018 - Wiley Online Library
Text mining is an important research direction, which involves several fields, such as
information retrieval, information extraction, and text categorization. In this paper, we …

Bioinformatics approaches for the functional interpretation of protein lists: from ontology term enrichment to network analysis

K Laukens, S Naulaerts, WV Berghe - Proteomics, 2015 - Wiley Online Library
The main result of a great deal of the published proteomics studies is a list of identified
proteins, which then needs to be interpreted in relation to the research question and existing …

GenCLiP 2.0: a web server for functional clustering of genes and construction of molecular networks based on free terms

JH Wang, LF Zhao, P Lin, XR Su, SJ Chen… - …, 2014 - academic.oup.com
Identifying biological functions and molecular networks in a gene list and how the genes
may relate to various topics is of considerable value to biomedical researchers. Here, we …

Retrospective side effect profiling of the metastatic melanoma combination therapy ipilimumab-nivolumab using adverse event data

TG Soldatos, A Dimitrakopoulou-Strauss, L Larribere… - Diagnostics, 2018 - mdpi.com
Recent studies suggest that combining nivolumab with ipilimumab is a more effective
treatment for melanoma patients, compared to using ipilimumab or nivolumab alone …

Prioritization of candidate genes for periodontitis using multiple computational tools

Y Zhan, R Zhang, H Lv, X Song, X Xu… - Journal of …, 2014 - Wiley Online Library
Background: Both genetic and environmental factors contribute to the development of
periodontitis. Genetic studies identified a variety of candidate genes for periodontitis. The …

A novel method to quantify gene set functional association based on gene ontology

S Lv, Y Li, Q Wang, S Ning, T Huang… - Journal of The …, 2012 - royalsocietypublishing.org
Numerous gene sets have been used as molecular signatures for exploring the genetic
basis of complex disorders. These gene sets are distinct but related to each other in many …

Metab2MeSH: annotating compounds with medical subject headings

MA Sartor, A Ade, Z Wright, D States, GS Omenn… - …, 2012 - academic.oup.com
Progress in high-throughput genomic technologies has led to the development of a variety of
resources that link genes to functional information contained in the biomedical literature …

CoCiter: an efficient tool to infer gene function by assessing the significance of literature co-citation

N Qiao, Y Huang, H Naveed, CD Green, JDJ Han - PloS one, 2013 - journals.plos.org
A routine approach to inferring functions for a gene set is by using function enrichment
analysis based on GO, KEGG or other curated terms and pathways. However, such analysis …

How to learn about gene function: text-mining or ontologies?

TG Soldatos, N Perdigão, NP Brown, KS Sabir… - Methods, 2015 - Elsevier
As the amount of genome information increases rapidly, there is a correspondingly greater
need for methods that provide accurate and automated annotation of gene function. For …