Obesity represents a major health problem in the United States and is associated with
increased prevalence of cardiovascular (CV) disease risk factors. Physical activity (PA) and …

Irisin is a myokine that leads to increased energy expenditure by stimulating the'browning'of
white adipose tissue. In the first description of this hormone, increased levels of circulating …

White adipose tissue (WAT) is an endocrine organ highly integrated in homeostasis and
capable of establishing ways of communicating and influencing multiple metabolic …

Introduction Irisin is a myokine/adipokine induced by the exercise in mice and humans,
which is proposed to induce “browning” of white adipose tissue, its primary target, thus …

Sedentary life style is considered to be an independent risk factor for many disorders,
including development of type 2 diabetes, obesity, immune dysfunction, asthma, and …

Context: Irisin is a recently identified exercise-induced myokine. However, the circulating
levels of irisin in response to different types of exercise in subjects with metabolic syndrome …

Appetite and body weight regulation are controlled by the central nervous system (CNS) in a
rather complicated manner. The human brain plays a central role in integrating internal and …

FNDC5/irisin has been recently postulated as beneficial in the treatment of obesity and
diabetes because it is induced in muscle by exercise, increasing energy expenditure …

The long-term effect of therapeutic diets in obesity treatment is a challenge at present. The
current study aimed to evaluate the long-term effect of a very low-calorie-ketogenic (VLCK) …

The prevalence of obesity continues to rise worldwide despite evidence-based public health
recommendations. The promise to adopt a healthy lifestyle is increasingly important for …