Clinical features of late-onset multiple sclerosis: a systematic review and meta-analysis

A Naseri, E Nasiri, MA Sahraian, S Daneshvar… - Multiple sclerosis and …, 2021 - Elsevier
Background Multiple sclerosis (MS) commonly affects young adults at the ages 20 to 40
years old, but it can onset at each age. Late-onset multiple sclerosis (LOMS) is defined as …

Radiological features of late-onset multiple sclerosis: A systematic review and meta-analysis

E Nasiri, A Sarkesh, AD Sorkhabi, A Naseri… - Journal of …, 2023 - Elsevier
Background Late-onset multiple sclerosis (LOMS) is most commonly defined as the onset of
the disease's presentations at age 50 or older. There is still much to discover about the …

Multiple sclerosis in older adults: the clinical profile and impact of interferon Beta treatment

A Shirani, Y Zhao, J Petkau, P Gustafson… - BioMed research …, 2015 - Wiley Online Library
Background. We examined (1) patient characteristics and disease‐modifying drug (DMD)
exposure in late‐onset (LOMS,≥ 50 years at symptom onset) versus adult‐onset (AOMS, 18 …

Late-onset multiple sclerosis in Iran: A report on demographic and disease characteristics

F Ghadiri, MA Sahraian, N Razazian, F Ashtari… - Multiple sclerosis and …, 2023 - Elsevier
Background Today, it is estimated that around 5% of multiple sclerosis (MS) patients are in
the late-onset category (age at disease onset≥ 50). Diagnosis and treatment in this group …

Is time to reach EDSS 6.0 faster in patients with late-onset versus young-onset multiple sclerosis?

R Alroughani, S Akhtar, S Ahmed, R Behbehani… - PLoS …, 2016 - journals.plos.org
Background & Objectives Published natural history data on late-onset of multiple sclerosis
are limited. We aimed to assess the risk of attaining EDSS 6.0 among patients with late …

[HTML][HTML] Late onset multiple sclerosis: concerns in aging patients

CBC Lotti, ASB Oliveira, DB Bichuetti… - Arquivos de neuro …, 2017 - SciELO Brasil
Late onset multiple sclerosis (LOMS) is when the first symptom starts after 50 years of age,
representing 4.5% of multiple sclerosis (MS) patients. This study describes the clinical …

Aging and neurological diseases

M Kowalska, M Owecki, M Prendecki… - Senescence …, 2017 - books.google.com
Current knowledge indicates that the aging process starts with subclinical changes at the
molecular level. These include the accumulation of mutations, telomere attrition, and …

Interleukin-33 plasma levels in patients with relapsing-remitting multiple sclerosis

F Alsahebfosoul, I Rahimmanesh, M Shajarian… - Biomolecular …, 2017 - degruyter.com
Cytokines are implicated in the immunopathogenesis of multiple sclerosis (MS). Interleukin
(IL)-33, one of the recently discovered members of the IL-1 superfamily, is a dual functional …

Ongoing increase in incidence and prevalence of multiple sclerosis in south-eastern Iran: A three decade study

A Moghtaderi, M Shahidi-Pourakbari, S Izadi… - Multiple Sclerosis and …, 2023 - Elsevier
Background Prevalence of multiple sclerosis has been increased during the last decades
throughout the world. Epidemiological studies could improve our understanding relating to …

[HTML][HTML] Psychosocial and medical determinants of health-related quality of life in patients with relapsing-remitting multiple sclerosis

IR Boogar, S Talepasand, M Jabari - Archives of Neuropsychiatry, 2018 - ncbi.nlm.nih.gov
Methods: In this cross-sectional descriptive study, 193 patients with relapsing-remitting
multiple sclerosis were selected by compliance sampling method among the patients who …