DNA methylation profiling: an emerging paradigm for cancer diagnosis
A Papanicolau-Sengos, K Aldape - Annual Review of Pathology …, 2022 - annualreviews.org
Histomorphology has been a mainstay of cancer diagnosis in anatomic pathology for many
years. DNA methylation profiling is an additional emerging tool that will serve as an adjunct …
years. DNA methylation profiling is an additional emerging tool that will serve as an adjunct …
Multimodal data fusion for cancer biomarker discovery with deep learning
Technological advances have made it possible to study a patient from multiple angles with
high-dimensional, high-throughput multiscale biomedical data. In oncology, massive …
high-dimensional, high-throughput multiscale biomedical data. In oncology, massive …
Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression
Cervical squamous cell carcinoma (CESC) is a prototypical human cancer with well-
characterized pathological stages of initiation and progression. However, high-resolution …
characterized pathological stages of initiation and progression. However, high-resolution …
Microbiome analyses of blood and tissues suggest cancer diagnostic approach
Systematic characterization of the cancer microbiome provides a unique opportunity to
develop cancer diagnostics that exploit non-human, microbial-derived molecules in a major …
develop cancer diagnostics that exploit non-human, microbial-derived molecules in a major …
Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine
The Hippo pathway is an evolutionarily conserved signalling pathway with key roles in
organ development, epithelial homeostasis, tissue regeneration, wound healing and …
organ development, epithelial homeostasis, tissue regeneration, wound healing and …
[HTML][HTML] Biological and clinical aspects of HPV-related cancers
KA Szymonowicz, J Chen - Cancer biology & medicine, 2020 - ncbi.nlm.nih.gov
Cancer-related diseases represent the second overall cause of death worldwide. Human
papilloma virus (HPV) is an infectious agent which is mainly sexually transmitted and may …
papilloma virus (HPV) is an infectious agent which is mainly sexually transmitted and may …
Pan-cancer image-based detection of clinically actionable genetic alterations
Molecular alterations in cancer can cause phenotypic changes in tumor cells and their
microenvironment. Routine histopathology tissue slides, which are ubiquitously available …
microenvironment. Routine histopathology tissue slides, which are ubiquitously available …
Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials
Abstract Characterization and integration of the genome, epigenome, transcriptome,
proteome and metabolome of different datasets is difficult owing to a lack of ground truth …
proteome and metabolome of different datasets is difficult owing to a lack of ground truth …
[HTML][HTML] An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
J Liu, T Lichtenberg, KA Hoadley, LM Poisson… - Cell, 2018 - cell.com
Summary For a decade, The Cancer Genome Atlas (TCGA) program collected
clinicopathologic annotation data along with multi-platform molecular profiles of more than …
clinicopathologic annotation data along with multi-platform molecular profiles of more than …
miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplay
Cervical cancer (CC) is the primary cause of cancer deaths in underdeveloped countries.
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …