Microbial production of natural and non-natural flavonoids: pathway engineering, directed evolution and systems/synthetic biology
In this review, we address recent advances made in pathway engineering, directed
evolution, and systems/synthetic biology approaches employed in the production and …
evolution, and systems/synthetic biology approaches employed in the production and …
Recent advances in systems metabolic engineering tools and strategies
Highlights•Microbial cell factories are becoming important in sustainable chemical
production.•Systems metabolic engineering allows efficient microbial cell factory …
production.•Systems metabolic engineering allows efficient microbial cell factory …
Plant cell cultures: biofactories for the production of bioactive compounds
Plants have long been exploited as a sustainable source of food, flavors, agrochemicals,
colors, therapeutic proteins, bioactive compounds, and stem cell production. However, plant …
colors, therapeutic proteins, bioactive compounds, and stem cell production. However, plant …
Phytostilbenes as agrochemicals: Biosynthesis, bioactivity, metabolic engineering and biotechnology
P Jeandet, A Vannozzi, E Sobarzo-Sánchez… - Natural product …, 2021 - pubs.rsc.org
Covering: 1976 to 2020. Although constituting a limited chemical family, phytostilbenes
represent an emblematic group of molecules among natural compounds. Ever since their …
represent an emblematic group of molecules among natural compounds. Ever since their …
Engineering plant secondary metabolism in microbial systems
Engineering Plant Secondary Metabolism in Microbial Systems | Plant Physiology | Oxford
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Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis
Hydroxypropionic acid (3HP), an important three carbon (C3) chemical, is designated as
one of the top platform chemicals with an urgent need for improved industrial production …
one of the top platform chemicals with an urgent need for improved industrial production …
Development of a growth coupled and multi-layered dynamic regulation network balancing malonyl-CoA node to enhance (2S)-naringenin biosynthesis in Escherichia …
Metabolic heterogeneity and dynamic changes in metabolic fluxes are two inherent
characteristics of microbial fermentation that limit the precise control of metabolisms, often …
characteristics of microbial fermentation that limit the precise control of metabolisms, often …
Repurposing type III polyketide synthase as a malonyl-CoA biosensor for metabolic engineering in bacteria
Malonyl-CoA is an important central metabolite for the production of diverse valuable
chemicals including natural products, but its intracellular availability is often limited due to …
chemicals including natural products, but its intracellular availability is often limited due to …
Construction of a Corynebacterium glutamicum platform strain for the production of stilbenes and (2S)-flavanones
N Kallscheuer, M Vogt, A Stenzel, J Gätgens, M Bott… - Metabolic …, 2016 - Elsevier
Corynebacterium glutamicum is an important organism in industrial biotechnology for the
microbial production of bulk chemicals, in particular amino acids. However, until now activity …
microbial production of bulk chemicals, in particular amino acids. However, until now activity …
Biobased organic acids production by metabolically engineered microorganisms
Highlights•The use of inexpensive carbon sources is urgently needed for citric acid
production.•Low-pH process benefits lactic acid production.•Different strains and processes …
production.•Low-pH process benefits lactic acid production.•Different strains and processes …