Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …

Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

Sequestration of malaria-parasite-infected erythrocytes in the microvasculature of organs is
thought to be a significant cause of pathology. Cerebral malaria (CM) is a major …

The sequestration of Plasmodium falciparum–infected red blood cells (irbcs) in the
microvasculature of organs is associated with severe disease; correspondingly, the …

Genetic manipulation of malaria parasites would revolutionize the study of this group of
pathogens and have implications for vaccine and drug development. This report describes …

Background The clinical symptoms of malaria are caused by the asexual replication of
Plasmodium parasites in the blood of the vertebrate host. To spread to new hosts, however …

Species of malaria parasites that infect rodents provide models for the study of the biology of
malaria parasites that infect humans. In this article, Chris Janse and Andy Waters describe …

The Plasmodium cell cycle, wherein millions of parasites differentiate and proliferate, occurs
in synchrony with the vertebrate host's circadian cycle. The underlying mechanisms are …

DNA contents of individual stages of Plasmodium berghei were measured by direct
microfluorometry after Feulgen-pararosaniline (SO 2) staining. Sporozoites, intra-erythrocytic …

Recent reviews (Feachem et al.; Alonso et al.) have concluded that in order to have a
sustainable impact on the global burden of malaria, it is essential that we knowingly reduce …