Phantom auditory perception—tinnitus—is a symptom of many pathologies. Although there
are a number of theories postulating certain mechanisms of its generation, none have been …

In mammals, environmental sounds stimulate the auditory receptor, the cochlea, via
vibrations of the stapes, the innermost of the middle ear ossicles. These vibrations produce …

Mammalian hearing depends on an amplification process involving prestin, a voltage-
sensitive motor protein that enables cochlear outer hair cells (OHCs) to change length and …

The outer and inner hair cells of the mammalian cochlea perform different functions. In
response to changes in membrane potential, the cylindrical outer hair cell rapidly alters its …

The voltage-dependent motor protein prestin (also known as SLC26A5) is responsible for
the electromotive behaviour of outer-hair cells and underlies the cochlear amplifier …

Sensorineural hearing loss (SNHL) can either be genetically inherited or acquired as a
result of aging, noise exposure, or ototoxic drugs. Although the precise pathophysiological …

The senses of hearing and equilibrium depend on sensory receptors called hair cells which
can detect motions of atomic dimensions and respond more than 100,000 times a second …

Normal hearing depends on sound amplification within the mammalian cochlea. The
amplification, without which the auditory system is effectively deaf, can be traced to the …

Outer hair cell electromotility is a rapid, force generating, length change in response to
electrical stimulation. DC electrical pulses either elongate or shorten the cell and sinusoidal …

Since the late 197Os, drastic advances have been made in the field of peripheral auditory
research. Among these are the results from intracellular hair cell recording (138, 572, 573) …