Introduction. Clinical complications in sickle cell anemia (SCA) are heterogeneous and
involve several molecules. It has been suggested that SCA individuals present a …

Introduction Vitamin D levels in adult black Americans with sickle cell disease (SCD) are
comparatively lower than those found in the general population of black Americans. The …

Background: Haemoglobin genotype is an important blood component that determines
haemoglobinopathies. Distribution of haemoglobin variants was investigated among the Ika …

Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory
events. The TGF‐β pathway is known to play a role in immune response, angiogenesis …

Abstract Background/Aim: Painful vaso-occlusive crisis (VOC) is the most frequent
complication of sickle cell disease. The cause of VOC is believed to be ischemic tissue injury …

Background: Sickle cell disease (SCD) is an autosomal inherited disorder of haemoglobin
caused by a substitution of thymidine for adenine (GAG-GTG) of the βchain that results in the …

Background/Aim: 痛苦的疾患危机 (VOC) 是最 frequent complication of sickle cell disease.
The cause of VOC is believed to be ischemic tissue injury from the obstruction of blood flow …

Background/objective: The role of foetal haemoglobin (HbF) on the modulation of clinical
manifestations in sickle cell disease is well known but there is inconsistency as to the levels …