Epigenetic age prediction

DJ Simpson, T Chandra - Aging cell, 2021 - Wiley Online Library
Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …

Recent progress, methods and perspectives in forensic epigenetics

A Vidaki, M Kayser - Forensic Science International: Genetics, 2018 - Elsevier
Forensic epigenetics, ie, investigating epigenetics variation to resolve forensically relevant
questions unanswerable with standard forensic DNA profiling has been gaining substantial …

Refining epigenetic prediction of chronological and biological age

E Bernabeu, DL McCartney, DA Gadd, RF Hillary… - Genome Medicine, 2023 - Springer
Background Epigenetic clocks can track both chronological age (cAge) and biological age
(bAge). The latter is typically defined by physiological biomarkers and risk of adverse health …

[HTML][HTML] DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing

A Vidaki, D Ballard, A Aliferi, TH Miller… - Forensic Science …, 2017 - Elsevier
The ability to estimate the age of the donor from recovered biological material at a crime
scene can be of substantial value in forensic investigations. Aging can be complex and is …

Predicting age from the transcriptome of human dermal fibroblasts

JG Fleischer, R Schulte, HH Tsai, S Tyagi, A Ibarra… - Genome biology, 2018 - Springer
Biomarkers of aging can be used to assess the health of individuals and to study aging and
age-related diseases. We generate a large dataset of genome-wide RNA-seq profiles of …

Classification of flat bands according to the band-crossing singularity of Bloch wave functions

JW Rhim, BJ Yang - Physical Review B, 2019 - APS
We show that flat bands can be categorized into two distinct classes, that is, singular and
nonsingular flat bands, by exploiting the singular behavior of their Bloch wave functions in …

Facial genetics: a brief overview

S Richmond, LJ Howe, S Lewis, E Stergiakouli… - Frontiers in …, 2018 - frontiersin.org
Historically, craniofacial genetic research has understandably focused on identifying the
causes of craniofacial anomalies and it has only been within the last 10 years, that there has …

[HTML][HTML] Strategies for analyzing bisulfite sequencing data

K Wreczycka, A Gosdschan, D Yusuf, B Grüning… - Journal of …, 2017 - Elsevier
DNA methylation is one of the main epigenetic modifications in the eukaryotic genome; it
has been shown to play a role in cell-type specific regulation of gene expression, and …

DNA methylation-based age prediction using massively parallel sequencing data and multiple machine learning models

A Aliferi, D Ballard, MD Gallidabino, H Thurtle… - Forensic Science …, 2018 - Elsevier
The field of DNA intelligence focuses on retrieving information from DNA evidence that can
help narrow down large groups of suspects or define target groups of interest. With recent …

[PDF][PDF] Forensic individual age estimation with DNA: from initial approaches to methylation tests

A Freire-Aradas, C Phillips… - Forensic Sci Rev, 2017 - forensicsciencereview.com
Individual age estimation is a key factor in forensic science analysis that can provide very
useful information applicable to criminal, legal, and anthropological investigations. Forensic …