Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications

MN Huda, M Nafiujjaman, IG Deaguero… - ACS biomaterials …, 2021 - ACS Publications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …

[HTML][HTML] The role of exosomes and their applications in cancer

Y Zhou, Y Zhang, H Gong, S Luo, Y Cui - International journal of …, 2021 - mdpi.com
Exosomes are very small extracellular vesicles secreted by multiple cell types and are
extensively distributed in various biological fluids. Recent research indicated that exosomes …

[HTML][HTML] Non-melanoma skin cancers: Biological and clinical features

M Cives, F Mannavola, L Lospalluti, MC Sergi… - International Journal of …, 2020 - mdpi.com
Non-melanoma skin cancers (NMSCs) include basal cell carcinoma (BCC), squamous cell
carcinoma (SCC) and Merkel cell carcinoma (MCC). These neoplasms are highly diverse in …

[HTML][HTML] Exosomal proteins and lipids as potential biomarkers for lung cancer diagnosis, prognosis, and treatment

MT Hsu, YK Wang, YJ Tseng - Cancers, 2022 - mdpi.com
Simple Summary Exosomes (or extracellular vesicles) are known to mediate intercellular
communication and to transmit molecular signals between cells. Molecules carried by …

Clinical impact of exosomes in colorectal cancer metastasis

S Ghosh, R Dhar, G Gurudas Shivji, D Dey… - ACS Applied Bio …, 2023 - ACS Publications
Cancer is a complex deadly disease that has caused a global health crisis in recent epochs.
Colorectal cancer (CRC) is the third most common malignant gastrointestinal disease. It has …

[HTML][HTML] Enhancing clinical potential of liquid biopsy through a multi-omic approach: A systematic review

G Di Sario, V Rossella, ES Famulari, A Maurizio… - Frontiers in …, 2023 - frontiersin.org
In the last years, liquid biopsy gained increasing clinical relevance for detecting and
monitoring several cancer types, being minimally invasive, highly informative and replicable …

Colorectal cancer-derived exosomal miR-106b-3p promotes metastasis by down-regulating DLC-1 expression

H Liu, Y Liu, P Sun, K Leng, Y Xu, L Mei, P Han… - Clinical …, 2020 - portlandpress.com
Cancer-derived exosomal miRNAs play an important role in the development of metastasis,
but the effects and underlying mechanisms remain unclear. In the present study, we …

[HTML][HTML] Urinary biomarkers in bladder cancer: where do we stand and potential role of extracellular vesicles

MC Oliveira, HR Caires, MJ Oliveira, A Fraga… - Cancers, 2020 - mdpi.com
Extracellular vesicles (EVs) are small membrane vesicles released by all cells and involved
in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and …

[HTML][HTML] The extracellular matrix in colorectal cancer and its metastatic settling–Alterations and biological implications

S Karlsson, H Nyström - Critical reviews in oncology/hematology, 2022 - Elsevier
Colorectal cancer (CRC) remains one of the most common cancers worldwide. Metastatic
disease is ultimately fatal when incurable. Cancer research has evolved to take the …

Exosomes: The protagonists in the tale of colorectal cancer?

DK Nabariya, R Pallu, VR Yenuganti - Biochimica et Biophysica Acta (BBA) …, 2020 - Elsevier
Exosomes, which facilitate intercellular communication, antigen presentation and shuttling of
biological agents, were initially thought as the cell's garbage cargo but today, after about 40 …