RNA interference (RNAi) is one of the most importantly protective phenomena forming from
the process combating against virus. Since its high efficiency for silencing the expression of …

The Southeast Asian outbreak of the highly lethal avian influenza A HSN1 infection in
humans is unlikely to abate because of the enormous number of backyard farms providing …

PAMAM dendrimers for efficient siRNA delivery and potent gene silencing - Chemical
Communications (RSC Publishing) DOI:10.1039/B601381C Royal Society of Chemistry View …

A novel triblock poly (amido amine)-poly (ethylene glycol)-poly-l-lysine (PAMAM-PEG-PLL)
nanocarrier was designed, synthesized, and evaluated for the delivery of siRNA. The design …

A novel cancer targeted, internally cationic and surface neutral polyamidoamine (PAMAM)
dendrimer, was designed, synthesized, and evaluated as a nanocarrier for the targeted …

A novel internally quaternized and surface-acetylated poly (amidoamine) generation four
dendrimer (QPAMAM-NHAc) was synthesized and evaluated for intracellular delivery of …

Angiogenesis, or new blood vessel formation, is critical for the growth and spread of tumors.
Multiple phases of this process, namely, migration, proliferation, morphogenesis, and …

Ribozymes and deoxyribozymes (collectively referred to as nucleic acid enzymes) can be
designed to cleave substrate mRNAs in a sequence‐specific manner, and thus represent a …

ABSTRACT RNA interference (RNAi) is an adaptive defense mechanism triggered by
double-stranded RNA (dsRNA). It is a powerful reverse genetic tool that has been widely …

RNA interference (RNAi) holds great promise for the treatment of inherited and acquired
diseases, provided that safe and efficient delivery systems are available. Herein we report …