Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Dietary curcumin: correlation between bioavailability and health potential

M Dei Cas, R Ghidoni - Nutrients, 2019 - mdpi.com
The yellow pigment curcumin, extracted from turmeric, is a renowned polyphenol with a
broad spectrum of health properties such as antioxidant, anti-inflammatory, anti-cancer …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Mitochondria as potential targets in Alzheimer disease therapy: an update

G Cenini, W Voos - Frontiers in pharmacology, 2019 - frontiersin.org
Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …

Immunomodulators inspired by nature: a review on curcumin and echinacea

M Catanzaro, E Corsini, M Rosini, M Racchi, C Lanni - Molecules, 2018 - mdpi.com
The immune system is an efficient integrated network of cellular elements and chemicals
developed to preserve the integrity of the organism against external insults and its correct …

The multifaceted role of curcumin in advanced nanocurcumin form in the treatment and management of chronic disorders

P Tagde, P Tagde, F Islam, S Tagde, M Shah… - Molecules, 2021 - mdpi.com
Curcumin is the primary polyphenol in turmeric's curcuminoid class. It has a wide range of
therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic …

Antioxidants in Alzheimer's disease: Current therapeutic significance and future prospects

P Pritam, R Deka, A Bhardwaj, R Srivastava, D Kumar… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …

Multifaceted role of phyto-derived polyphenols in nanodrug delivery systems

Z Chen, MA Farag, Z Zhong, C Zhang, Y Yang… - Advanced drug delivery …, 2021 - Elsevier
As naturally occurring bioactive products, several lines of evidence have shown the potential
of polyphenols in the medical intervention of various diseases, including tumors …

Curcumin's nanomedicine formulations for therapeutic application in neurological diseases

B Salehi, D Calina, AO Docea, N Koirala… - Journal of Clinical …, 2020 - mdpi.com
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …

Curcumin combination chemotherapy: The implication and efficacy in cancer

BL Tan, ME Norhaizan - Molecules, 2019 - mdpi.com
Many chemotherapeutic drugs have been used for the treatment of cancer, for instance,
doxorubicin, irinotecan, 5-fluorouracil, cisplatin, and paclitaxel. However, the effectiveness of …