[HTML][HTML] Gut dysfunction in Parkinson's disease

A Mukherjee, A Biswas, SK Das - World journal of …, 2016 - ncbi.nlm.nih.gov
Early involvement of gut is observed in Parkinson's disease (PD) and symptoms such as
constipation may precede motor symptoms. α-Synuclein pathology is extensively evident in …

Weight loss and malnutrition in patients with Parkinson's disease: current knowledge and future prospects

K Ma, N Xiong, Y Shen, C Han, L Liu… - Frontiers in aging …, 2018 - frontiersin.org
Parkinson's Disease (PD) is currently considered a systemic neurodegenerative disease
manifested with not only motor but also non-motor symptoms. In particular, weight loss and …

Analysis of gut microbiota in patients with Parkinson's disease

VA Petrov, IV Saltykova, IA Zhukova… - Bulletin of experimental …, 2017 - Springer
Gut microbiota of patients with Parkinson's disease and healthy volunteers was analyzed by
the method of high throughput 16S rRNA sequencing of bacterial genomes. In patients with …

Integrated analyses of microbiome and longitudinal metabolome data reveal microbial-host interactions on sulfur metabolism in Parkinson's disease

J Hertel, AC Harms, A Heinken, F Baldini, CC Thinnes… - Cell reports, 2019 - cell.com
Parkinson's disease (PD) exhibits systemic effects on the human metabolism, with emerging
roles for the gut microbiome. Here, we integrate longitudinal metabolome data from 30 drug …

Neuroendocrine abnormalities in Parkinson's disease

E De Pablo-Fernández, DP Breen… - Journal of Neurology …, 2017 - jnnp.bmj.com
Neuroendocrine abnormalities are common in Parkinson's disease (PD) and include
disruption of melatonin secretion, disturbances of glucose, insulin resistance and bone …

Association between change in body mass index, unified Parkinson's disease rating scale scores, and survival among persons with Parkinson disease: secondary …

AMA Wills, A Pérez, J Wang, X Su, J Morgan… - JAMA …, 2016 - jamanetwork.com
Importance Greater body mass index (BMI, calculated as weight in kilograms divided by
height in meters squared) is associated with improved survival among persons with …

DUOGLOBE: one‐year outcomes in a real‐world study of levodopa carbidopa intestinal gel for Parkinson's disease

DG Standaert, J Aldred… - Movement Disorders …, 2021 - Wiley Online Library
Background Levodopa‐carbidopa intestinal gel (LCIG) is an established treatment for
improving motor and some non‐motor symptoms (NMS) in patients with advanced …

Parkinson's disease and sugar intake—reasons for and consequences of a still unclear craving

J Haas, D Berg, A Bosy-Westphal, E Schaeffer - Nutrients, 2022 - mdpi.com
Lately, studies have shown that patients with Parkinson's disease (PD) report a strong
craving for sweets and consume significantly more fast-acting carbohydrates than healthy …

Clinical trajectories and biomarkers for weight variability in early Parkinson's disease

D Urso, DJ van Wamelen, L Batzu, V Leta… - npj Parkinson's …, 2022 - nature.com
Unexplained weight changes that occur in Parkinson's disease (PD), are often neglected
and remain a poorly understood non-motor feature in patients with PD. A specific 'Park …

Progressive and accelerated weight and body fat loss in Parkinson's disease: A three-year prospective longitudinal study

VW Yong, YJ Tan, YD Ng, XY Choo… - Parkinsonism & related …, 2020 - Elsevier
Introduction Although weight loss is common in Parkinson's disease (PD), longitudinal
studies assessing weight and body composition changes are limited. Methods In this three …