Alzheimer's disease (AD) is characterized by an imbalance between production and
clearance of amyloid-β (Aβ) species. Aβ peptides can transform structurally from monomers …

Alzheimer's disease (AD) challenges our society with an annual estimated cost of $1.08
trillion in the United States alone by 2050. 1 AD is a progressive irreversible neurological …

This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …

The cascade of amyloid formation relates to multiple complex events at the molecular level.
Previous research has established amyloid plaque deposition as the leading cause of …

Alzheimer's disease (AD) is the most common type of neurodegenerative disorder, typically
causing dementia along aging. AD is mainly characterized by a pathological extracellular …

Amyloid oligomers have emerged as the most toxic species of amyloid-β (Aβ). This
hypothesis might explain the lack of correlation between amyloid plaques and memory …

The present advances in biology are related to progress in genomics, proteomics, and other
“-omics”, including glycomics, working with a large amount of data regarding human and …

Protein misfolding and metal ion dyshomeostasis are believed to underlie numerous
neurodegenerative diseases, including Alzheimer's disease (AD). The pathological hallmark …

This tutorial review presents descriptions of two amyloidogenic proteins, amyloid-β (Aβ)
peptides and islet amyloid polypeptide (IAPP), whose misfolding propensities are implicated …

Amyloid peptides (AMYs) and antimicrobial peptides (AMPs) are considered as the two
distinct families of peptides, characterized by their unique sequences, structures, biological …