Diabetic kidney disease remains the most common cause of end-stage kidney disease in
the world. Despite reductions in incidence rates of myocardial infarction and stroke in people …

The global prevalence of diabetes mellitus was estimated to be 463 million people in 2019
and is predicted to rise to 700 million by 2045. The associated financial and societal costs of …

背景临床上20%~ 40% 的2 型糖尿病患者进展为糖尿病肾脏病(DKD), DKD
的主要临床表现为微量尿蛋白和肾功能改变, 肾小球滤过率(GFR) 是反映肾功能的重要指标 …

The clinical significance of albuminuria in diabetic subjects and the impact of its reduction on
the main cardiorenal outcomes by different drug classes are among the most interesting …

In recent decades, the prevalence of diabetic kidney disease has remained stable and
appears to be a wide heterogeneity. Normoalbuminuric diabetes with renal insufficiency …

Background Studies of progression of kidney dysfunction typically focus on renal
replacement therapy or percentage decline in estimated glomerular filtration rate (eGFR) as …

Background Normoalbuminuric diabetic kidney disease (NADKD) is a newly defined DKD,
the clinical features and pathogenesis for which are still being understood. This study aimed …

A panel of cytokines and growth factors, mediating low-grade inflammation and fibrosis, was
assessed in patients with type 2 diabetes (T2D) and different patterns of chronic kidney …

Background A sodium restriction diet is a key component of chronic kidney disease (CKD)
management. However, the efficacy of its use in patients with diabetic kidney disease (DKD) …

Background and study aims—Albuminuria, defined as an enhanced urine
albumin/creatinine ratio (ACR) on a spot sample, is a validated biomarker of glomerular …