Biofilms and vulvovaginal candidiasis

C Rodríguez-Cerdeira, MC Gregorio… - Colloids and Surfaces B …, 2019 - Elsevier
Candida species, including C. albicans, are part of the mucosal flora of most healthy women,
and inhabit the gastrointestinal and genitourinary tracts. Under favourable conditions, they …

The pathobiology of human fungal infections

GD Brown, ER Ballou, S Bates, EM Bignell… - Nature Reviews …, 2024 - nature.com
Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

[HTML][HTML] Candida albicans exploits N-acetylglucosamine as a gut signal to establish the balance between commensalism and pathogenesis

D Yang, M Zhang, C Su, B Dong, Y Lu - Nature Communications, 2023 - nature.com
Candida albicans is a benign member of gut microbiota, but also causes life-threatening
disseminated infections, suggesting that this fungus commensalism has evolved with …

[HTML][HTML] Adapting to survive: How Candida overcomes host-imposed constraints during human colonization

R Alves, C Barata-Antunes, M Casal, AJP Brown… - PLoS …, 2020 - journals.plos.org
Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

We need to talk about Candida tropicalis: Virulence factors and survival mechanisms

MM Dos Santos, K Ishida - Medical mycology, 2023 - academic.oup.com
Candida tropicalis is a notable species of the Candida genus representing an impressive
epidemiology in tropical regions, especially in South America and Asia, where India already …

Multiple alternative carbon pathways combine to promote Candida albicans stress resistance, immune interactions, and virulence

RB Williams, MC Lorenz - MBio, 2020 - Am Soc Microbiol
The phagocytic cells of the innate immune system are an essential first line of antimicrobial
defense, and yet Candida albicans, one of the most problematic fungal pathogens, is …

The interplay between gut bacteria and the yeast Candida albicans

JC Pérez - Gut Microbes, 2021 - Taylor & Francis
The fungus Candida albicans is a ubiquitous member of the human gut microbiota.
Hundreds or thousands of bacterial taxa reside together with this fungus in the intestine …

Transcriptional control of hyphal morphogenesis in Candida albicans

S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …

Interesting antifungal drug targets in the central metabolism of Candida albicans

S Wijnants, J Vreys, P Van Dijck - Trends in Pharmacological Sciences, 2022 - cell.com
To treat infections caused by Candida albicans, azoles, polyenes, and echinocandins are
used. However, resistance occurs against all three, so there is an urgent need for new …

[HTML][HTML] From Jekyll to Hyde: The Yeast–Hyphal Transition of Candida albicans

EWL Chow, LM Pang, Y Wang - Pathogens, 2021 - mdpi.com
Candida albicans is a major fungal pathogen of humans, accounting for 15% of nosocomial
infections with an estimated attributable mortality of 47%. C. albicans is usually a benign …