Enzymatically oxidized lipids are a specific group of biomolecules that function as key
signaling mediators and hormones, regulating various cellular and physiological processes …

Cholesterol homeostasis is critical for normal growth and development. In addition to being
a major membrane lipid, cholesterol has multiple biological functions. These roles include …

The biological activity of steroid hormones is regulated at the pre-receptor level by several
enzymes including 17 beta-hydroxysteroid dehydrogenases (17 beta-HSD). The latter are …

Alzheimer's disease (AD) is an age-dependent neurodegenerative disease that causes
progressive cognitive impairment. The initiation and progression of AD has been linked to …

17beta-Hydroxysteroid dehydrogenases (17beta-HSDs) are important enzymes in steroid
metabolism. Long known members of the protein family seemed to be well characterised …

17β-Hydroxysteroid dehydrogenases (17β-HSDs) catalyze the NAD (P)(H) dependent
oxidoreduction at C17 oxo/β-hydroxyl groups of androgen and estrogen hormones. This …

17β-Hydroxysteroid dehydrogenases (17β-HSDs) belong to the family of short chain
dehydrogenases/reductases (SDRs) and aldoketo-reductases (AKRs). Some of the …

Advanced medullary thyroid cancers (MTCs) are now being treated with drugs that inhibit
receptor tyrosine kinases, many of which involved in angiogenesis. Response rates vary …

The short-chain dehydrogenase/reductase (SDR) superfamily represents one of the largest
protein superfamilies known to date. Enzymes of this family usually catalyse NAD (P)(H) …

Background Saturated fatty acids can be detrimental to human health and have received
considerable attention in recent years. Several studies using taurine breeds showed the …