Antimicrobial multidrug resistance: clinical implications for infection management in critically ill patients

G Kalın, E Alp, A Chouaikhi, C Roger - Microorganisms, 2023 - mdpi.com
The increasing incidence of antimicrobial resistance (AMR) worldwide represents a serious
threat in the management of sepsis. Due to resistance to the most common antimicrobials …

New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care

AM Peri, A Stewart, A Hume, A Irwin… - Current Infectious Disease …, 2021 - Springer
Abstract Purpose of Review The aim of this article is to review current and emerging
microbiological techniques that support the rapid diagnosis of bacterial infections in critically …

Antimicrobial susceptibility testing: An updated primer for clinicians in the era of antimicrobial resistance: Insights from the Society of Infectious Diseases Pharmacists

E Wenzler, M Maximos, TE Asempa… - … : The Journal of …, 2023 - Wiley Online Library
Antimicrobial susceptibility testing (AST) is a critical function of the clinical microbiology
laboratory and is essential for optimizing care of patients with infectious diseases …

Clinical impact of the accelerate PhenoTest® BC system on patients with gram-negative bacteremia and high risk of antimicrobial resistance: a prospective before …

T Brosh-Nissimov, A Tzur, D Grupel, A Cahan… - Annals of Clinical …, 2023 - Springer
Abstract Background The Accelerate PhenoTest® BC system (AXDX) is a novel assay for
rapid bacterial identification and antimicrobial susceptibility (AST). We report an evaluation …

Management of gram-negative bloodstream infections in the era of rapid diagnostic testing: impact with and without antibiotic stewardship

KC Claeys, EL Heil, S Hitchcock… - Open Forum …, 2020 - academic.oup.com
Abstract Background Verigene Blood-Culture Gram-Negative is a rapid diagnostic test
(RDT) that detects gram-negatives (GNs) and resistance within hours from gram stain. The …

Real-world impact of the Accelerate PhenoTest BC Kit on patients with bloodstream infections in the Improving Outcomes and Antimicrobial Stewardship Study: a …

AA Bhalodi, SH MacVane, B Ford, D Ince… - Clinical infectious …, 2022 - academic.oup.com
Abstract Background Bloodstream infections (BSIs) are a leading cause of morbidity and
mortality. The Improving Outcomes and Antimicrobial Stewardship study seeks to evaluate …

Implementation of a rapid phenotypic susceptibility platform for gram-negative bloodstream infections with paired antimicrobial stewardship intervention: is the juice …

ED Robinson, AM Stilwell, AE Attai… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Implementation of the Accelerate PhenoTM Gram-negative platform
(RDT) paired with antimicrobial stewardship program (ASP) intervention projects to improve …

Evaluation of the performance and clinical impact of a Rapid phenotypic susceptibility testing method directly from positive blood culture at a Pediatric Hospital

TT Truong, K Mongkolrattanothai, II Flores… - Journal of Clinical …, 2022 - Am Soc Microbiol
Bloodstream infection poses a significant medical emergency that necessitates timely
administration of appropriate antibiotics. Standard laboratory workup for antimicrobial …

[HTML][HTML] Getting up to speed: rapid pathogen and antimicrobial resistance diagnostics in sepsis

MP Liborio, PNA Harris, C Ravi, AD Irwin - Microorganisms, 2024 - mdpi.com
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Time to receive effective therapy is a primary determinant of mortality in patients …

Mortality due to multidrug-resistant gram-negative bacteremia in an endemic region: No better than a toss of a coin

O Tsachouridou, D Pilalas, S Nanoudis, A Antoniou… - Microorganisms, 2023 - mdpi.com
The incidence of multidrug-resistant (MDR) bloodstream infections (BSIs) is associated with
high morbidity and mortality. Little evidence exists regarding the epidemiology of BSIs and …