The neonatal hemostatic system is strikingly different from that of adults. Among other
differences, neonates exhibit hyporeactive platelets and decreased levels of coagulation …

The neonatal hemostatic system is different from that of adults. The differences in levels of
procoagulant and anticoagulant factors and the evolving equilibrium in secondary …

Abstract The Platelets for Neonatal Thrombocytopenia (PlaNeT-2) trial reported an
unexpected overall benefit of a prophylactic platelet transfusion threshold of 25× 109/L …

The aim of the study was to develop and validate a prediction model for hemorrhage in
critically ill neonates which combines rotational thromboelastometry (ROTEM) parameters …

Importance Platelet transfusion is commonly performed in infants to correct severe
thrombocytopenia or prevent bleeding. Exploring the associations of platelet transfusion …

We conducted a systematic review aiming to summarize the data on the current hemorrhage
prediction models and evaluate their potential for generalized application in the neonatal …

Red blood cell (RBC) and platelet transfusions are frequently administered to neonates. Up
to 90% of extremely low birth weight infants and 58% of preterm infants (< 32 weeks …

Importance Infants born extremely preterm receive transfusions at higher platelet count
thresholds than older children and adults due to concerns for intracranial hemorrhage. A …

Critically ill neonates constitute a very fragile population at high risk of bleeding and in need
of transfusions. Prediction scores and bleeding assessment tools, which could help …

Objective To describe the incidence of major bleeds according to different platelet counts in
very preterm infants, and to explore whether this association is influenced by other risk …