Description: Although approximately 85 million units of red blood cells (RBCs) are
transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the …

Objective To compare the benefit and harm of restrictive versus liberal transfusion strategies
to guide red blood cell transfusions. Design Systematic review with meta-analyses and trial …

Importance Red blood cell transfusion is a common medical intervention with benefits and
harms. Objective To provide recommendations for use of red blood cell transfusion in adults …

Importance More than 100 million units of blood are collected worldwide each year, yet the
indication for red blood cell (RBC) transfusion and the optimal length of RBC storage prior to …

Objective To develop evidence-based clinical practice recommendations regarding
transfusion practices in non-bleeding, critically ill adults. Design A task force involving 13 …

Background There is considerable uncertainty regarding the optimal haemoglobin threshold
for the use of red blood cell (RBC) transfusions in anaemic patients. Blood is a scarce …

Objective To compare patient outcomes of restrictive versus liberal blood transfusion
strategies in patients with cardiovascular disease not undergoing cardiac surgery. Design …

Background The optimal haemoglobin threshold for use of red blood cell (RBC) transfusions
in anaemic patients remains an active field of research. Blood is a scarce resource, and in …

Background Several new trials evaluating transfusion strategies in patients with
cardiovascular disease have recently been published, increasing the number of enrolled …

Background There is accumulating evidence that restricting blood transfusions improves
outcomes, with newer trials showing greater benefit from more restrictive strategies. We …