Neuroprotective potential of Moringa oleifera mediated by NF‐kB/Nrf2/HO‐1 signaling pathway: A review

M Mundkar, A Bijalwan, D Soni… - Journal of Food …, 2022 - Wiley Online Library
Moringa oleifera is a traditional Indian herb belonging to the Moringaceae family, it is
commonly known as the horse‐radish tree, drumstick, or sahajna. In developing countries …

The role of isothiocyanate-rich plants and supplements in neuropsychiatric disorders: A review and update

M Ramakrishnan, JW Fahey, AW Zimmerman… - Frontiers in …, 2024 - frontiersin.org
Neuroinflammation in response to environmental stressors is an important common pathway
in a number of neurological and psychiatric disorders. Responses to immune-mediated …

Transient demyelination causes long‐term cognitive impairment, myelin alteration and network synchrony defects

O Mercier, PP Quilichini, K Magalon, F Gil, A Ghestem… - Glia, 2024 - Wiley Online Library
In the adult brain, activity‐dependent myelin plasticity is required for proper learning and
memory consolidation. Myelin loss, alteration, or even subtle structural modifications can …

Potential utility of natural products against oxidative stress in animal models of multiple sclerosis

Z Zha, S Liu, Y Liu, C Li, L Wang - Antioxidants, 2022 - mdpi.com
Multiple sclerosis (MS) is an autoimmune-mediated degenerative disease of the central
nervous system (CNS) characterized by immune cell infiltration, demyelination and axonal …

Cognitive‐Enhancing, Ex Vivo Antilipid Peroxidation and Qualitative Phytochemical Evaluation of the Aqueous and Methanolic Stem Bark Extracts of Lonchocarpus …

G Moriasi, A Ireri, M Ngugi - Biochemistry Research …, 2020 - Wiley Online Library
Over 50 million persons are living with cognitive deficits worldwide, with over 80% of these
individuals living in the developing world. The number of affected persons is projected to go …

Neuroprotective effects of melatonin during demyelination and remyelination stages in a mouse model of multiple sclerosis

HA Abo Taleb, BS Alghamdi - Journal of molecular neuroscience, 2020 - Springer
Multiple sclerosis (MS) is a progressive chronic inflammatory autoimmune disease of the
myelin sheath, and melatonin is a powerful antioxidant and anti-inflammatory agent. The …

Nrf2 deficiency increases oligodendrocyte loss, demyelination, neuroinflammation and axonal damage in an MS animal model

A Nellessen, S Nyamoya, A Zendedel, A Slowik… - Metabolic Brain …, 2020 - Springer
Oxidative stress is a pathophysiological hallmark of many CNS diseases, among multiple
sclerosis (MS). Accordingly, boosting the astrocytic transcription factor nuclear factor E2 …

Moringa oleifera-supplemented diet protect against cortico-hippocampal neuronal degeneration in scopolamine-induced spatial memory deficit in mice: role of oxido …

SA Onasanwo, VO Adamaigbo, OG Adebayo… - Metabolic Brain …, 2021 - Springer
The therapeutic and pharmacological management of Alzheimer's disease (AD) is generally
considered a major concern in ethnomedicine. Moreover, plant-based foods containing …

Comparative neuroprotective potential of nanoformulated and free resveratrol against cuprizone-induced demyelination in rats

SAM El-Sayed, GI Fouad, MZ Rizk, HH Beherei… - Molecular …, 2024 - Springer
Demyelination is a frequent yet crippling neurological disease associated with multiple
sclerosis (MS). The cuprizone (CZ) model, which causes demyelination through oxidative …

Biochanin A improves memory decline and brain pathology in cuprizone-induced mouse model of multiple sclerosis

RS Aldhahri, BS Alghamdi, NA Alzahrani… - Behavioral …, 2022 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system characterized by the demyelination of nerves, neural degeneration …