A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues

M Risseeuw, M Overhand, GWJ Fleet, MI Simone - Amino acids, 2013 - Springer
This compendium focuses on functionalised sugar amino acids (SAAs) and their 3-to 6-
membered nitrogen heterocyclic and carbocyclic analogues. The main benefit of using SAAs …

Computer-aided design of amino acid-based therapeutics: A review

T Farhadi, SMR Hashemian - Drug design, development and …, 2018 - Taylor & Francis
During the last two decades, the pharmaceutical industry has progressed from detecting
small molecules to designing biologic-based therapeutics. Amino acid-based drugs are a …

Design and characterization of a membrane permeable N‐methyl amino acid‐containing peptide that inhibits Aβ1–40 fibrillogenesis

DJ Gordon, R Tappe… - The Journal of peptide …, 2002 - Wiley Online Library
Alzheimer's disease, Huntington's disease and prion diseases are part of a growing list of
diseases associated with formation of β‐sheet containing fibrils. In a previous publication …

Target-directed organocatalysis: A direct asymmetric catalytic approach to chiral propargylic and allylic fluorides

H Jiang, A Falcicchio, KL Jensen… - Journal of the …, 2009 - ACS Publications
A simple, direct one-pot organocatalytic approach to the formation of optically active
propargylic fluorides is presented. The approach is based on organocatalytic α-fluorination …

Peptide δ‐turn: Literature survey and recent progress

C Toniolo, M Crisma, A Moretto… - … A European Journal, 2015 - Wiley Online Library
Among the various types of α‐peptide folding motifs, δ‐turn, which requires a central cis‐
amide disposition, has been one of the least extensively investigated. In particular, this main …

Synthesis and characterization of a melanoma-targeted fluorescence imaging probe by conjugation of a melanocortin 1 receptor (MC1R) specific ligand

NK Tafreshi, X Huang, VE Moberg… - Bioconjugate …, 2012 - ACS Publications
The incidence of malignant melanoma is rising more rapidly than that of any other cancer in
the United States. The melanocortin 1 receptor (MC1R) is overexpressed in most human …

Bypassing the proline/thiazoline requirement of the macrocyclase PatG

E Oueis, H Stevenson, M Jaspars… - Chemical …, 2017 - pubs.rsc.org
Biocatalysis is a fast developing field in which an enzyme's natural capabilities are
harnessed or engineered for synthetic chemistry. The enzyme PatG is an extremely …

Electronic circular dichroism of peptides

C Toniolo, F Formaggio… - … in stereochemical analysis …, 2012 - Wiley Online Library
Peptides are of great importance in biology for their many activities: hormones, intracellular
signals, neurotransmitters, immunogens, antibiotics, toxins, and so on. The biological …

Array-based technologies and their applications in proteomics.

GY Chen, M Uttamchandani, RY Lue, ML Lesaicherrea… - 2003 - scholarbank.nus.edu.sg
Array-based technologies and their applications in proteomics. | ScholarBank@NUS Skip
navigation NUS Repository NUS Libraries NUS Home Research Outputs View research …

New synthesis of 7-azabicyclo [2.2. 1] heptane-1-carboxylic acid

A Avenoza, C Cativiela, JH Busto… - Tetrahedron, 2001 - Elsevier
New synthesis of 7-azabicyclo[2.2.1]heptane-1-carboxylic acid - ScienceDirect Skip to main
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