For more than a century, chemists have endeavored to discover and develop reaction
processes that enable the selective oxidation of hydrocarbons. In the 1970s, Abramovitch …

The addition of an allylic organometallic compound to a carbonyl compound or an imine is of
great synthetic interest because in this reaction together with a new functionality (hydroxyl or …

With their mechanistic novelty and various modalities of reactivity, transition metal
unsaturated carbene (alkenylidene) complexes have emerged as versatile intermediates for …

Transition metal-catalyzed C–H amination at positions adjacent to double bonds and
carbonyl groups is discussed in this critical review. While the focus will center on the recent …

The development of mild, general, and selective transition metal catalyzed methods for the
functionalization of carbon–hydrogen bonds represents a significant current challenge in …

The propargylation reaction is one of the most important fundamental reactions in organic
synthesis. It features mild reaction conditions, a tolerance of a diverse range of functional …

The significant progress made in the area of transition metal-catalyzed nitrene transfer into C–
H or CC bonds mediated by iodine (III) oxidants has been translated into many elegant …

An asymmetric synthesis of the fugu fish poison,(−)-tetrodotoxin, is described. The route to
this extraordinary target employs a number of unique transformations, foremost of which are …

Reaction methods for selective C–H amination are finding ever-increasing utility for the
preparation of nitrogen-derived fine chemicals. This brief account highlights the remarkable …

A detailed mechanistic investigation of the intramolecular dirhodium tetracarboxylate-
catalyzed sulfamate ester C–H amination reaction is presented. These studies provide …