Lateral flow test engineering and lessons learned from COVID-19
The acceptability and feasibility of large-scale testing with lateral flow tests (LFTs) for clinical
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …
Antibody tests for identification of current and past infection with SARS‐CoV‐2
Background The diagnostic challenges associated with the COVID‐19 pandemic resulted in
rapid development of diagnostic test methods for detecting SARS‐CoV‐2 infection. Serology …
rapid development of diagnostic test methods for detecting SARS‐CoV‐2 infection. Serology …
Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants
The COVID-19 pandemic highlights the need for diagnostics that can be rapidly adapted
and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome …
and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome …
Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2
The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for
controlling disease transmission. Here, we develop SHINE (Streamlined Highlighting of …
controlling disease transmission. Here, we develop SHINE (Streamlined Highlighting of …
Detection of COVID-19: A review of the current literature and future perspectives
T Ji, Z Liu, GQ Wang, X Guo, C Lai, H Chen… - Biosensors and …, 2020 - Elsevier
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to the coronavirus disease 2019 (COVID-19) worldwide pandemic. This unprecedented …
to the coronavirus disease 2019 (COVID-19) worldwide pandemic. This unprecedented …
CRISPR‐Cas biochemistry and CRISPR‐based molecular diagnostics
Polymerase chain reaction (PCR)‐based nucleic acid testing has played a critical role in
disease diagnostics, pathogen surveillance, and many more. However, this method requires …
disease diagnostics, pathogen surveillance, and many more. However, this method requires …
[HTML][HTML] Genetics and genomics of SARS-CoV-2: A review of the literature with the special focus on genetic diversity and SARS-CoV-2 genome detection
The outbreak of 2019-novel coronavirus disease (COVID-19), caused by SARS-CoV-2,
started in late 2019; in a short time, it has spread rapidly all over the world. Although some …
started in late 2019; in a short time, it has spread rapidly all over the world. Although some …
CRISPR-Cas for genome editing: classification, mechanism, designing and applications
S Bhatia, SK Yadav - International Journal of Biological Macromolecules, 2023 - Elsevier
Clustered regularly interspersed short pallindromic repeats (CRISPR) and CRISPR
associated proteins (Cas) system (CRISPR-Cas) came into light as prokaryotic defence …
associated proteins (Cas) system (CRISPR-Cas) came into light as prokaryotic defence …
An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing
Extensive testing is essential to break the transmission of SARS-CoV-2, which causes the
ongoing COVID-19 pandemic. Here, we present a CRISPR-based diagnostic assay that is …
ongoing COVID-19 pandemic. Here, we present a CRISPR-based diagnostic assay that is …
An update on molecular diagnostics for COVID-19
KU Islam, J Iqbal - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
A novel strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) disease
(COVID-19) has been recently identified as an infectious disease affecting the respiratory …
(COVID-19) has been recently identified as an infectious disease affecting the respiratory …