Endothelial colony-forming cells (ECFCs) are vascular resident and circulating endothelial
cell subtypes with potent angiogenic capacity, a hierarchy of single-cell clonogenic …

Pulmonary hypertension (PH) is a severe condition characterized by elevated pressure in
the pulmonary artery, where metabolic and mitochondrial dysfunction may contribute to its …

Although half of hypertensive patients have hypertensive parents, known hypertension-
related human loci identified by genome-wide analysis explain only 3% of hypertension …

Background: HIV is associated with an increased risk for emphysema. Matrix
metalloproteinase 9 (MMP-9) is a lung tissue remodeling enzyme associated with …

The risk of developing pulmonary hypertension (PH) in people living with HIV is at least 300-
fold higher than in the general population, and illicit drug use further potentiates the …

The intricate relationship between chronic lung diseases and viral infections is a significant
concern in respiratory medicine. We explore how pre-existing lung conditions, including …

Purpose: Ischemia-reperfusion injury (IRI) is a major challenge in lung transplantation often
causing graft dysfunction and chronic airway illnesses in recipients. To prevent potential …

People living with HIV and who receive antiretroviral therapy have a significantly improved
lifespan, compared to the early days without therapy. Unfortunately, persisting viral …

Although overall survival rates of patients infected with human immunodeficiency virus (HIV)
have been significantly improved by antiretroviral therapy (ART), chronic comorbidities …

December 1, 2021, is “World AIDS Day,” reminding us that HIV infection is still widespread
and that many of its long-term effects can be deadly. One of these complications is its effect …