▪ Abstract The shikimate pathway links metabolism of carbohydrates to biosynthesis of
aromatic compounds. In a sequence of seven metabolic steps, phosphoenolpyruvate and …

Mononuclear iron enzymes can tightly bind non-activating metals. How do cells avoid
mismetallation? The model bacterium Escherichia coli may control its metal pools so that …

The shikimate pathway was discovered as the biosynthetic route to the aromatic amino acids
phenylalanine, tyrosine, and tryptophan through the classic studies of Bernhard Davis and …

The plant shikimate pathway directs bulk carbon flow toward biosynthesis of aromatic amino
acids (AAAs, ie tyrosine, phenylalanine, and tryptophan) and numerous aromatic …

Covering: 1997 to 2023 The shikimate pathway is the metabolic process responsible for the
biosynthesis of the aromatic amino acids phenylalanine, tyrosine, and tryptophan. Seven …

Nickel is now recognized as an essential trace element for bacteria, plants, animals and
humans. 1-6 While the role of this metal in animal biochemistry is still not well defined, to …

This chapter describes in detail the genes and proteins of Escherichia coli involved in the
biosynthesis and transport of the three aromatic amino acids tyrosine, phenylalanine, and …

The aromatic compounds such as aromatic amino acids, vitamin K and ubiquinone are
important prerequisites for the metabolism of an organism. All organisms can synthesize …

In all sequenced genomes, a large fraction of predicted genes encodes proteins of unknown
biochemical function and up to 15% of the genes with “known” function are mis-annotated …

Background: In microorganisms and plants the first step in the common pathway leading to
the biosynthesis of aromatic compounds is the stereospecific condensation of …