Although the therapeutic efficacy and commercial success of monoclonal antibodies (mAbs)
are tremendous, the design and discovery of new candidates remain a time and cost …

The convenience of subcutaneous (SC) administration and the increasing interest in
monoclonal antibody (mAb)-based therapies for chronic diseases, hint their potential for SC …

Biopharmaceuticals have revolutionized the field of medicine in the types of active
ingredient molecules and treatable indications. Adoption of Quality by Design and Process …

Solid-state is the preferred choice for storage of protein therapeutics to improve stability and
preserve the biological activity by decreasing the physical and chemical degradation …

Monoclonal antibodies (mAbs) are one of the most important classes of therapeutic proteins,
which are used to treat a wide number of diseases (eg, oncology, inflammation and …

Effective translation of breakthrough discoveries into innovative products in the clinic
requires proactive mitigation or elimination of several drug development challenges. These …

The purpose of this work is to provide an in silico molecular rationale of the role eventually
played by currently circulating mutations in the receptor binding domain of the SARS-CoV-2 …

Tangential flow filtration is an efficient membrane separation technology utilized across a
wide range of industries for separation and purification applications. The requirement of …

Monoclonal antibodies (mAbs) are an important class of therapeutic agents approved for the
therapy of many types of malignancies. However, in certain cases applications of …

Pharmacological and genetic studies over the past decade have established the follicle-
stimulating hormone (FSH) as an actionable target for diseases affecting millions, namely …