Changes in the composition of the gut microbiota are associated with many human
diseases. So far, however, we have failed to define homeostasis or dysbiosis by the …

Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …

Epidemiological studies have indicated an association between statin use and reduced
incidence of colorectal cancer (CRC), and work in preclinical models has demonstrated a …

Cardiometabolic diseases have become a leading cause of morbidity and mortality globally.
They have been tightly linked to microbiome taxonomic and functional composition, with diet …

The prevalence of metabolic diseases, including obesity, dyslipidemia, type 2 diabetes
mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), is a severe burden in human …

The mechanisms by which the early-life microbiota protects against environmental factors
that promote childhood obesity remain largely unknown. Using a mouse model in which …

Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

Type 2 diabetes mellitus (T2DM), one of the fastest growing metabolic diseases, has been
characterized by metabolic disorders including hyperglycemia, hyperlipidemia and insulin …

Morbidity and mortality of cardiovascular diseases (CVDs) are exceedingly high worldwide.
Researchers have found that the occurrence and development of CVDs are closely related …

The gut microbiota plays a role in many human diseases, but high-throughput sequence
analysis does not provide a straightforward path for defining healthy microbial communities …